Genome-wide association study of Crohn's disease in Koreans revealed three new susceptibility loci and common attributes of genetic susceptibility across ethnic populations

Objective Crohn's disease (CD) is an intractable inflammatory bowel disease (IBD) of unknown cause. Recent meta-analysis of the genome-wide association studies (GWAS) and Immunochip data identified 163 susceptibility loci to IBD in Caucasians, however there are limited studies in other populati...

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Veröffentlicht in:	Gut 2014-01, Vol.63 (1), p.80-87
Hauptverfasser:	Yang, Suk-Kyun, Hong, Myunghee, Zhao, Wanting, Jung, Yusun, Baek, Jiwon, Tayebi, Naeimeh, Kim, Kyung Mo, Ye, Byong Duk, Kim, Kyung-Jo, Park, Sang Hyoung, Lee, Inchul, Lee, Eun-Ju, Kim, Won Ho, Cheon, Jae Hee, Kim, Young-Ho, Jang, Byung Ik, Kim, Hyun-Soo, Choi, Jai Hyun, Koo, Ja Seol, Lee, Ji Hyun, Jung, Sung-Ae, Lee, Yeoun Joo, Jang, Joo Young, Shin, Hyoung Doo, Kang, Daehee, Youn, Hee-Shang, Liu, Jianjun, Song, Kyuyoung
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Asian Continental Ancestry Group - genetics Asian people Autophagy-Related Proteins Carrier Proteins - genetics Case-Control Studies Chromosomes Consortia Crohn Disease - ethnology Crohn Disease - genetics Crohn's disease Dual-Specificity Phosphatases - genetics Female Genes Genetic Markers Genetic Predisposition to Disease - ethnology Genetics Genome-Wide Association Study Genomes Genotyping Techniques GTPase-Activating Proteins - genetics Humans Inflammatory bowel disease Kruppel-Like Transcription Factors - genetics Logistic Models Male Membrane Proteins - genetics Odds Ratio Polymorphism, Single Nucleotide Population Principal components analysis Quality control Republic of Korea RNA Splicing Factors SMN Complex Proteins - genetics Software Studies White people Young Adult
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