Expression of estrogen and progesterone receptors and estrogen metabolizing enzymes in different breast cancer cell lines

Prolonged exposure to estrogens is a significant risk factor for the development of breast cancer. Estrogens exert carcinogenic effects by stimulating cell proliferation or through oxidative metabolism that forms DNA-damaging species. In the present study, we aimed to provide a better understanding...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Chemico-biological interactions 2011-05, Vol.191 (1), p.206-216
Hauptverfasser:	Hevir, N., Trošt, N., Debeljak, N., Lanišnik Rižner, T.
Format:	Artikel
Sprache:	eng
Schlagworte:	17β-Hydroxysteroid dehydrogenases (17β-HSDs) aerobiosis Aldo-keto reductases (AKRs) Aromatase arylsulfatase breast neoplasms Breast Neoplasms - enzymology Breast Neoplasms - genetics Breast Neoplasms - metabolism Breast Neoplasms - pathology carcinogenicity Catechol-O-methyl transferase (COMT) Cell Line, Tumor cell proliferation Enzymes - genetics Enzymes - metabolism estradiol estrogen receptors Estrogens - biosynthesis Estrogens - metabolism gene expression Gene Expression Regulation, Neoplastic genes Humans metastasis plant growth substances progesterone receptors Receptors, Estrogen - genetics Receptors, Progesterone - genetics risk factors Sulfatase Sulfotransferases UDP Glucuronosyl transferase (UGT) unspecific monooxygenase
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!