Short-Term Exposure to Nickel Alters the Adult Rat Brain Antioxidant Status and the Activities of Crucial Membrane-Bound Enzymes: Neuroprotection by L-Cysteine

Nickel (Ni) is an environmental pollutant towards which human exposure can be both occupational (mainly through inhalation) and dietary (through water and food chain-induced bioaccumulation). The aim of this study was to investigate the effects of short-term Ni-administration (as NiCl2, 13 mg/kg) on...

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Veröffentlicht in:	Biological trace element research 2011-12, Vol.143 (3), p.1673-1681
Hauptverfasser:	Liapi, Charis, Zarros, Apostolos, Theocharis, Stamatios, Voumvourakis, Konstantinos, Anifantaki, Foteini, Gkrouzman, Elena, Mellios, Zois, Skandali, Nikolina, Al-Humadi, Hussam, Tsakiris, Stylianos
Format:	Artikel
Sprache:	eng
Schlagworte:	acetylcholinesterase Acetylcholinesterase - metabolism adults Animals Antioxidants Antioxidants - metabolism Bioaccumulation Biochemistry Biomedical and Life Sciences Biotechnology Brain Brain - drug effects Brain - enzymology Brain - metabolism breathing Ca(2+) Mg(2+)-ATPase - metabolism chronic exposure cysteine Cysteine - pharmacology decapitation Enzymes humans Inhalation Life Sciences Male Membranes Neurology Neuroprotective Agents - pharmacology neuroprotective effect neurotoxicity Nickel Nickel - toxicity Nutrition Oncology Rats Rats, Wistar Rodents sodium-potassium-exchanging ATPase Sodium-Potassium-Exchanging ATPase - metabolism
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