Water-restraint stress enhances methamphetamine-induced cardiotoxicity

Methamphetamine (MAP) and stress both cause a variety of cardiovascular problems. Stress also increases stimulant drug-seeking or drug-taking behavior by both humans and animals. In addition to the physiological effects on circulation, metabolism, and excretion, stress affects subject's respons...

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Veröffentlicht in:	Chemico-biological interactions 2011-03, Vol.190 (1), p.54-61
Hauptverfasser:	Tomita, Masafumi, Katsuyama, Hironobu, Watanabe, Yoko, Hidaka, Kazuo, Yoshitome, Kei, Miyaishi, Satoru, Ishikawa, Takaki, Shinone, Kotaro, Nata, Masayuki
Format:	Artikel
Sprache:	eng
Schlagworte:	ambient temperature animal experimentation Animals cardioprotective effect Cardiotoxicity Central Nervous System Stimulants - toxicity Chaperonin 60 - genetics Chaperonin 60 - metabolism drugs excretion Fatty Acid-Binding Proteins - metabolism Heart - drug effects Heat shock protein heat shock proteins hosts HSP70 Heat-Shock Proteins - genetics HSP70 Heat-Shock Proteins - metabolism HSP90 Heat-Shock Proteins - genetics HSP90 Heat-Shock Proteins - metabolism humans Immersion interleukin-10 Interleukin-10 - metabolism interleukin-6 Interleukin-6 - metabolism metabolism Methamphetamine Methamphetamine - toxicity Mice muscles Myocardia Myocardium - metabolism Myocardium - pathology RNA Stress, Physiological Temperature Tumor Necrosis Factor-alpha - metabolism Water-restraint stress
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