Recent advances on ocular Demodex infestation
PURPOSE OF REVIEWTo summarize recent advances on ocular Demodex infestation. RECENT FINDINGSDemodex infestation is a potential cause of ocular surface inflammation. The pathogenesis of Demodex in eliciting ocular surface inflammation has been further clarified. Cliradex is currently the treatment of...
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| Veröffentlicht in: | Current opinion in ophthalmology 2015-07, Vol.26 (4), p.295-300 |
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| creator | Cheng, Anny M.S Sheha, Hosam Tseng, Scheffer C.G |
| description | PURPOSE OF REVIEWTo summarize recent advances on ocular Demodex infestation.
RECENT FINDINGSDemodex infestation is a potential cause of ocular surface inflammation. The pathogenesis of Demodex in eliciting ocular surface inflammation has been further clarified. Cliradex is currently the treatment of choice, it comprises the most active ingredient of tea tree oil, that is terpinen-4-ol, which helps eradicate Demodex mites and reduce ocular surface inflammation.
SUMMARYOcular demodicosis is a common but overlooked eye disease that manifests a number of morbidities. Demodex folliculorum causes chronic anterior blepharitis whereas Demodex brevis causes posterior blepharitis, meibomian gland dysfunction, recurrent chalazia, and refractory keratoconjunctivitis. The lash sampling and microscopic counting method and in-vivo confocal microscopy are key diagnostic methods. Cliradex shows promising potential to reduce Demodex counts with additional antibacterial, antifungal, and anti-inflammatory actions. |
| doi_str_mv | 10.1097/ICU.0000000000000168 |
| format | Article |
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RECENT FINDINGSDemodex infestation is a potential cause of ocular surface inflammation. The pathogenesis of Demodex in eliciting ocular surface inflammation has been further clarified. Cliradex is currently the treatment of choice, it comprises the most active ingredient of tea tree oil, that is terpinen-4-ol, which helps eradicate Demodex mites and reduce ocular surface inflammation.
SUMMARYOcular demodicosis is a common but overlooked eye disease that manifests a number of morbidities. Demodex folliculorum causes chronic anterior blepharitis whereas Demodex brevis causes posterior blepharitis, meibomian gland dysfunction, recurrent chalazia, and refractory keratoconjunctivitis. The lash sampling and microscopic counting method and in-vivo confocal microscopy are key diagnostic methods. Cliradex shows promising potential to reduce Demodex counts with additional antibacterial, antifungal, and anti-inflammatory actions.</description><identifier>ISSN: 1040-8738</identifier><identifier>EISSN: 1531-7021</identifier><identifier>DOI: 10.1097/ICU.0000000000000168</identifier><identifier>PMID: 26058028</identifier><language>eng</language><publisher>United States: Copyright Wolters Kluwer Health, Inc. All rights reserved</publisher><subject>Animals ; Anti-Infective Agents, Local - therapeutic use ; Blepharitis - diagnosis ; Blepharitis - parasitology ; Blepharitis - therapy ; Eye Infections, Parasitic - diagnosis ; Eye Infections, Parasitic - parasitology ; Eye Infections, Parasitic - therapy ; Humans ; Hygiene ; Meibomian Glands - parasitology ; Mite Infestations - diagnosis ; Mite Infestations - parasitology ; Mite Infestations - therapy ; Mites ; Tea Tree Oil - therapeutic use</subject><ispartof>Current opinion in ophthalmology, 2015-07, Vol.26 (4), p.295-300</ispartof><rights>Copyright © 2015 Wolters Kluwer Health, Inc. All rights reserved.</rights><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/26058028$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Cheng, Anny M.S</creatorcontrib><creatorcontrib>Sheha, Hosam</creatorcontrib><creatorcontrib>Tseng, Scheffer C.G</creatorcontrib><title>Recent advances on ocular Demodex infestation</title><title>Current opinion in ophthalmology</title><addtitle>Curr Opin Ophthalmol</addtitle><description>PURPOSE OF REVIEWTo summarize recent advances on ocular Demodex infestation.
RECENT FINDINGSDemodex infestation is a potential cause of ocular surface inflammation. The pathogenesis of Demodex in eliciting ocular surface inflammation has been further clarified. Cliradex is currently the treatment of choice, it comprises the most active ingredient of tea tree oil, that is terpinen-4-ol, which helps eradicate Demodex mites and reduce ocular surface inflammation.
SUMMARYOcular demodicosis is a common but overlooked eye disease that manifests a number of morbidities. Demodex folliculorum causes chronic anterior blepharitis whereas Demodex brevis causes posterior blepharitis, meibomian gland dysfunction, recurrent chalazia, and refractory keratoconjunctivitis. The lash sampling and microscopic counting method and in-vivo confocal microscopy are key diagnostic methods. Cliradex shows promising potential to reduce Demodex counts with additional antibacterial, antifungal, and anti-inflammatory actions.</description><subject>Animals</subject><subject>Anti-Infective Agents, Local - therapeutic use</subject><subject>Blepharitis - diagnosis</subject><subject>Blepharitis - parasitology</subject><subject>Blepharitis - therapy</subject><subject>Eye Infections, Parasitic - diagnosis</subject><subject>Eye Infections, Parasitic - parasitology</subject><subject>Eye Infections, Parasitic - therapy</subject><subject>Humans</subject><subject>Hygiene</subject><subject>Meibomian Glands - parasitology</subject><subject>Mite Infestations - diagnosis</subject><subject>Mite Infestations - parasitology</subject><subject>Mite Infestations - therapy</subject><subject>Mites</subject><subject>Tea Tree Oil - therapeutic use</subject><issn>1040-8738</issn><issn>1531-7021</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpNkE1LAzEQhoMotlb_gcgevaTmc5McpX4VCoLY85JkZ-lqdrdudq3-eyOt4FxmBh5meF6ELimZU2LUzXKxnpP_RXN9hKZUcooVYfQ4zUQQrBXXE3QW41tiBNHyFE1YTqQmTE8RfgEP7ZDZ8tO2HmLWtVnnx2D77A6aroSvrG4riIMd6q49RyeVDREuDn2G1g_3r4snvHp-XC5uV3hLdc4wtaTiAsqKgdNGcWeI5iCVodRyU2rpeSm01Mx7AsIbLRLiOHeOOapNzmfoen9323cfY_peNHX0EIJtoRtjkVRVLpKMSujVAR1dA2Wx7evG9t_Fn2ICxB7YdWGAPr6HcQd9sQEbhk2RMpFScYkZoZKotOLfKBn_AdwjYXg</recordid><startdate>201507</startdate><enddate>201507</enddate><creator>Cheng, Anny M.S</creator><creator>Sheha, Hosam</creator><creator>Tseng, Scheffer C.G</creator><general>Copyright Wolters Kluwer Health, Inc. All rights reserved</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>201507</creationdate><title>Recent advances on ocular Demodex infestation</title><author>Cheng, Anny M.S ; Sheha, Hosam ; Tseng, Scheffer C.G</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p1862-1a0f34edf2eb8973b9083e57911a39d85c3d48582cc0e4c9843b9b33bb2b18963</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Animals</topic><topic>Anti-Infective Agents, Local - therapeutic use</topic><topic>Blepharitis - diagnosis</topic><topic>Blepharitis - parasitology</topic><topic>Blepharitis - therapy</topic><topic>Eye Infections, Parasitic - diagnosis</topic><topic>Eye Infections, Parasitic - parasitology</topic><topic>Eye Infections, Parasitic - therapy</topic><topic>Humans</topic><topic>Hygiene</topic><topic>Meibomian Glands - parasitology</topic><topic>Mite Infestations - diagnosis</topic><topic>Mite Infestations - parasitology</topic><topic>Mite Infestations - therapy</topic><topic>Mites</topic><topic>Tea Tree Oil - therapeutic use</topic><toplevel>online_resources</toplevel><creatorcontrib>Cheng, Anny M.S</creatorcontrib><creatorcontrib>Sheha, Hosam</creatorcontrib><creatorcontrib>Tseng, Scheffer C.G</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Current opinion in ophthalmology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Cheng, Anny M.S</au><au>Sheha, Hosam</au><au>Tseng, Scheffer C.G</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Recent advances on ocular Demodex infestation</atitle><jtitle>Current opinion in ophthalmology</jtitle><addtitle>Curr Opin Ophthalmol</addtitle><date>2015-07</date><risdate>2015</risdate><volume>26</volume><issue>4</issue><spage>295</spage><epage>300</epage><pages>295-300</pages><issn>1040-8738</issn><eissn>1531-7021</eissn><abstract>PURPOSE OF REVIEWTo summarize recent advances on ocular Demodex infestation.
RECENT FINDINGSDemodex infestation is a potential cause of ocular surface inflammation. The pathogenesis of Demodex in eliciting ocular surface inflammation has been further clarified. Cliradex is currently the treatment of choice, it comprises the most active ingredient of tea tree oil, that is terpinen-4-ol, which helps eradicate Demodex mites and reduce ocular surface inflammation.
SUMMARYOcular demodicosis is a common but overlooked eye disease that manifests a number of morbidities. Demodex folliculorum causes chronic anterior blepharitis whereas Demodex brevis causes posterior blepharitis, meibomian gland dysfunction, recurrent chalazia, and refractory keratoconjunctivitis. The lash sampling and microscopic counting method and in-vivo confocal microscopy are key diagnostic methods. Cliradex shows promising potential to reduce Demodex counts with additional antibacterial, antifungal, and anti-inflammatory actions.</abstract><cop>United States</cop><pub>Copyright Wolters Kluwer Health, Inc. All rights reserved</pub><pmid>26058028</pmid><doi>10.1097/ICU.0000000000000168</doi><tpages>6</tpages></addata></record> |
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| subjects | Animals Anti-Infective Agents, Local - therapeutic use Blepharitis - diagnosis Blepharitis - parasitology Blepharitis - therapy Eye Infections, Parasitic - diagnosis Eye Infections, Parasitic - parasitology Eye Infections, Parasitic - therapy Humans Hygiene Meibomian Glands - parasitology Mite Infestations - diagnosis Mite Infestations - parasitology Mite Infestations - therapy Mites Tea Tree Oil - therapeutic use |
| title | Recent advances on ocular Demodex infestation |
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