Novel hybrid drilling protocol: evaluation for the implant healing - thermal changes, crestal bone loss, and bone-to-implant contact

Objectives To evaluate a new hybrid drilling protocol, by the analysis of thermal changes in vitro, and their effects in the crestal bone loss and bone‐to‐implant contact in vivo. Materials and Methods Temperature changes during simulated osteotomies with a hybrid drilling technique (biologic plus s...

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Veröffentlicht in:Clinical oral implants research 2015-07, Vol.26 (7), p.753-760
Hauptverfasser: Calvo-Guirado, José Luis, Delgado-Peña, Jorge, Maté-Sánchez, Jose E., Mareque Bueno, Javier, Delgado-Ruiz, Rafael Arcesio, Romanos, Georgios E.
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container_issue 7
container_start_page 753
container_title Clinical oral implants research
container_volume 26
creator Calvo-Guirado, José Luis
Delgado-Peña, Jorge
Maté-Sánchez, Jose E.
Mareque Bueno, Javier
Delgado-Ruiz, Rafael Arcesio
Romanos, Georgios E.
description Objectives To evaluate a new hybrid drilling protocol, by the analysis of thermal changes in vitro, and their effects in the crestal bone loss and bone‐to‐implant contact in vivo. Materials and Methods Temperature changes during simulated osteotomies with a hybrid drilling technique (biologic plus simplified) (test) versus an incremental drilling technique (control) were investigated. One hundred and twenty random osteotomies were performed (60 by group) in pig ribs up to 3.75‐mm‐diameter drill to a depth of 10 mm. Thermal changes and time were recorded by paired thermocouples. In a parallel experiment, bilateral mandibular premolars P2, P3, P4, and first molar M1 were extracted from six dogs. After 2‐month healing, implant sites were randomly prepared using either of the drilling techniques. Forty eight implants of 3.75 mm diameter and 10 mm length were inserted. The dogs were euthanized at 30 and 90 days, and crestal bone loss (CBL) and bone‐to‐implant contact (BIC) were evaluated. Results The control group showed maximum temperatures of 35.3°C ± 1.8°C, ΔT of 10.4°C, and a mean time of 100 s/procedure; meanwhile, the test group showed maximum temperatures of 36.7°C ± 1.2°C, ΔT of 8.1°C, and a mean time of 240 s/procedure. After 30 days, CBL values for both groups (test: 1.168 ± 0.194 mm; control: 1.181 ± 0.113 mm) and BIC values (test: 43 ± 2.8%; control: 45 ± 1.3%) were similar, without significant differences (P > 0.05). After 90 days, CBL (test: 1.173 ± 0.187 mm; control: 1.205 ± 0.122 mm) and BIC (test: 64 ± 3.3%; control: 64 ± 2.4%) values were similar, without significant differences (P > 0.05). The BIC values were increased at 90 days in both groups compared with the 30‐day period (P 
doi_str_mv 10.1111/clr.12341
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Materials and Methods Temperature changes during simulated osteotomies with a hybrid drilling technique (biologic plus simplified) (test) versus an incremental drilling technique (control) were investigated. One hundred and twenty random osteotomies were performed (60 by group) in pig ribs up to 3.75‐mm‐diameter drill to a depth of 10 mm. Thermal changes and time were recorded by paired thermocouples. In a parallel experiment, bilateral mandibular premolars P2, P3, P4, and first molar M1 were extracted from six dogs. After 2‐month healing, implant sites were randomly prepared using either of the drilling techniques. Forty eight implants of 3.75 mm diameter and 10 mm length were inserted. The dogs were euthanized at 30 and 90 days, and crestal bone loss (CBL) and bone‐to‐implant contact (BIC) were evaluated. Results The control group showed maximum temperatures of 35.3°C ± 1.8°C, ΔT of 10.4°C, and a mean time of 100 s/procedure; meanwhile, the test group showed maximum temperatures of 36.7°C ± 1.2°C, ΔT of 8.1°C, and a mean time of 240 s/procedure. After 30 days, CBL values for both groups (test: 1.168 ± 0.194 mm; control: 1.181 ± 0.113 mm) and BIC values (test: 43 ± 2.8%; control: 45 ± 1.3%) were similar, without significant differences (P &gt; 0.05). After 90 days, CBL (test: 1.173 ± 0.187 mm; control: 1.205 ± 0.122 mm) and BIC (test: 64 ± 3.3%; control: 64 ± 2.4%) values were similar, without significant differences (P &gt; 0.05). The BIC values were increased at 90 days in both groups compared with the 30‐day period (P &lt; 0.05). Conclusions Within the limitations of this study, the new hybrid protocol for the preparation of the implant bed without irrigation, increase the temperature similarly to the incremental conventional protocol, and requires twice the time for the completion of the drilling procedure in vitro. Crestal bone loss and bone‐to‐implant contact in the hybrid drilling protocol are comparable with the conventional drilling protocol and do not affect the osseointegration process in vivo.</description><identifier>ISSN: 0905-7161</identifier><identifier>EISSN: 1600-0501</identifier><identifier>DOI: 10.1111/clr.12341</identifier><identifier>PMID: 24502654</identifier><language>eng</language><publisher>Denmark: Blackwell Publishing Ltd</publisher><subject>Alveolar Process - surgery ; animal studies ; Animals ; Bicuspid ; biologic drilling ; Bone healing ; Bone loss ; bone-to-implant contact ; crestal bone loss ; Dental Implantation, Endosseous - methods ; Dental Implants ; Dentistry ; Dogs ; Drilling ; Healing ; histomorphometry ; Implants, Experimental ; In vivo methods and tests ; incremental drilling ; Mandible - surgery ; Osseointegration ; Osseointegration - physiology ; Osteotomy - methods ; Premolars ; Ribs - surgery ; Swine ; Temperature ; Temperature requirements ; Thermocouples ; Transplants &amp; implants ; Wound Healing - physiology</subject><ispartof>Clinical oral implants research, 2015-07, Vol.26 (7), p.753-760</ispartof><rights>2014 John Wiley &amp; Sons A/S. Published by John Wiley &amp; Sons Ltd</rights><rights>2014 John Wiley &amp; Sons A/S. Published by John Wiley &amp; Sons Ltd.</rights><rights>Copyright © 2015 John Wiley &amp; Sons A/S</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3911-a4241b5673e4225f9a2229701785404c25f3f52d60fd28999d79b64d85691e913</citedby><cites>FETCH-LOGICAL-c3911-a4241b5673e4225f9a2229701785404c25f3f52d60fd28999d79b64d85691e913</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fclr.12341$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fclr.12341$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1417,27924,27925,45574,45575</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24502654$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Calvo-Guirado, José Luis</creatorcontrib><creatorcontrib>Delgado-Peña, Jorge</creatorcontrib><creatorcontrib>Maté-Sánchez, Jose E.</creatorcontrib><creatorcontrib>Mareque Bueno, Javier</creatorcontrib><creatorcontrib>Delgado-Ruiz, Rafael Arcesio</creatorcontrib><creatorcontrib>Romanos, Georgios E.</creatorcontrib><title>Novel hybrid drilling protocol: evaluation for the implant healing - thermal changes, crestal bone loss, and bone-to-implant contact</title><title>Clinical oral implants research</title><addtitle>Clin. Oral Impl. Res</addtitle><description>Objectives To evaluate a new hybrid drilling protocol, by the analysis of thermal changes in vitro, and their effects in the crestal bone loss and bone‐to‐implant contact in vivo. Materials and Methods Temperature changes during simulated osteotomies with a hybrid drilling technique (biologic plus simplified) (test) versus an incremental drilling technique (control) were investigated. One hundred and twenty random osteotomies were performed (60 by group) in pig ribs up to 3.75‐mm‐diameter drill to a depth of 10 mm. Thermal changes and time were recorded by paired thermocouples. In a parallel experiment, bilateral mandibular premolars P2, P3, P4, and first molar M1 were extracted from six dogs. After 2‐month healing, implant sites were randomly prepared using either of the drilling techniques. Forty eight implants of 3.75 mm diameter and 10 mm length were inserted. The dogs were euthanized at 30 and 90 days, and crestal bone loss (CBL) and bone‐to‐implant contact (BIC) were evaluated. Results The control group showed maximum temperatures of 35.3°C ± 1.8°C, ΔT of 10.4°C, and a mean time of 100 s/procedure; meanwhile, the test group showed maximum temperatures of 36.7°C ± 1.2°C, ΔT of 8.1°C, and a mean time of 240 s/procedure. After 30 days, CBL values for both groups (test: 1.168 ± 0.194 mm; control: 1.181 ± 0.113 mm) and BIC values (test: 43 ± 2.8%; control: 45 ± 1.3%) were similar, without significant differences (P &gt; 0.05). After 90 days, CBL (test: 1.173 ± 0.187 mm; control: 1.205 ± 0.122 mm) and BIC (test: 64 ± 3.3%; control: 64 ± 2.4%) values were similar, without significant differences (P &gt; 0.05). The BIC values were increased at 90 days in both groups compared with the 30‐day period (P &lt; 0.05). Conclusions Within the limitations of this study, the new hybrid protocol for the preparation of the implant bed without irrigation, increase the temperature similarly to the incremental conventional protocol, and requires twice the time for the completion of the drilling procedure in vitro. Crestal bone loss and bone‐to‐implant contact in the hybrid drilling protocol are comparable with the conventional drilling protocol and do not affect the osseointegration process in vivo.</description><subject>Alveolar Process - surgery</subject><subject>animal studies</subject><subject>Animals</subject><subject>Bicuspid</subject><subject>biologic drilling</subject><subject>Bone healing</subject><subject>Bone loss</subject><subject>bone-to-implant contact</subject><subject>crestal bone loss</subject><subject>Dental Implantation, Endosseous - methods</subject><subject>Dental Implants</subject><subject>Dentistry</subject><subject>Dogs</subject><subject>Drilling</subject><subject>Healing</subject><subject>histomorphometry</subject><subject>Implants, Experimental</subject><subject>In vivo methods and tests</subject><subject>incremental drilling</subject><subject>Mandible - surgery</subject><subject>Osseointegration</subject><subject>Osseointegration - physiology</subject><subject>Osteotomy - methods</subject><subject>Premolars</subject><subject>Ribs - surgery</subject><subject>Swine</subject><subject>Temperature</subject><subject>Temperature requirements</subject><subject>Thermocouples</subject><subject>Transplants &amp; implants</subject><subject>Wound Healing - physiology</subject><issn>0905-7161</issn><issn>1600-0501</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kU9vFCEYxonR2LV68AsYEi-aSAsMfwZvZqOrcVOj0XgkDMN0qcywAlPdux9cutvtwUQuhCe_98nz8gDwlOAzUs-5DemM0IaRe2BBBMYIc0zugwVWmCNJBDkBj3K-whgL1aqH4IQyjqngbAH-XMRrF-Bm1yXfwz75EPx0CbcplmhjeA3dtQmzKT5OcIgJlo2DftwGMxW4cWYPoxs1jSZAuzHTpcuvoE0ulyp0cXIwxFwlM_X7JyoRHR1snIqx5TF4MJiQ3ZPb-xR8e_f26_I9Wn9afVi-WSPbKEKQYZSRjgvZOEYpH5ShlCqJiWw5w8xWqRk47QUeetoqpXqpOsH6lgtFnCLNKXhx8K3r_ZxrQj36bF2oWVycsyailYIRIXFFn_-DXsU5TTWdbjDnrVQN4ZV6eaBsqjsmN-ht8qNJO02wvqlG12r0vprKPrt1nLvR9XfksYsKnB-AXz643f-d9HL95WiJDhM-F_f7bsKkH7p-kuT6-8Wqxv28bunHlabNX2FPpac</recordid><startdate>201507</startdate><enddate>201507</enddate><creator>Calvo-Guirado, José Luis</creator><creator>Delgado-Peña, Jorge</creator><creator>Maté-Sánchez, Jose E.</creator><creator>Mareque Bueno, Javier</creator><creator>Delgado-Ruiz, Rafael Arcesio</creator><creator>Romanos, Georgios E.</creator><general>Blackwell Publishing Ltd</general><general>Wiley Subscription Services, Inc</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QO</scope><scope>7QP</scope><scope>8FD</scope><scope>FR3</scope><scope>K9.</scope><scope>P64</scope><scope>7X8</scope></search><sort><creationdate>201507</creationdate><title>Novel hybrid drilling protocol: evaluation for the implant healing - thermal changes, crestal bone loss, and bone-to-implant contact</title><author>Calvo-Guirado, José Luis ; Delgado-Peña, Jorge ; Maté-Sánchez, Jose E. ; Mareque Bueno, Javier ; Delgado-Ruiz, Rafael Arcesio ; Romanos, Georgios E.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3911-a4241b5673e4225f9a2229701785404c25f3f52d60fd28999d79b64d85691e913</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Alveolar Process - surgery</topic><topic>animal studies</topic><topic>Animals</topic><topic>Bicuspid</topic><topic>biologic drilling</topic><topic>Bone healing</topic><topic>Bone loss</topic><topic>bone-to-implant contact</topic><topic>crestal bone loss</topic><topic>Dental Implantation, Endosseous - methods</topic><topic>Dental Implants</topic><topic>Dentistry</topic><topic>Dogs</topic><topic>Drilling</topic><topic>Healing</topic><topic>histomorphometry</topic><topic>Implants, Experimental</topic><topic>In vivo methods and tests</topic><topic>incremental drilling</topic><topic>Mandible - surgery</topic><topic>Osseointegration</topic><topic>Osseointegration - physiology</topic><topic>Osteotomy - methods</topic><topic>Premolars</topic><topic>Ribs - surgery</topic><topic>Swine</topic><topic>Temperature</topic><topic>Temperature requirements</topic><topic>Thermocouples</topic><topic>Transplants &amp; implants</topic><topic>Wound Healing - physiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Calvo-Guirado, José Luis</creatorcontrib><creatorcontrib>Delgado-Peña, Jorge</creatorcontrib><creatorcontrib>Maté-Sánchez, Jose E.</creatorcontrib><creatorcontrib>Mareque Bueno, Javier</creatorcontrib><creatorcontrib>Delgado-Ruiz, Rafael Arcesio</creatorcontrib><creatorcontrib>Romanos, Georgios E.</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Biotechnology Research Abstracts</collection><collection>Calcium &amp; Calcified Tissue Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Clinical oral implants research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Calvo-Guirado, José Luis</au><au>Delgado-Peña, Jorge</au><au>Maté-Sánchez, Jose E.</au><au>Mareque Bueno, Javier</au><au>Delgado-Ruiz, Rafael Arcesio</au><au>Romanos, Georgios E.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Novel hybrid drilling protocol: evaluation for the implant healing - thermal changes, crestal bone loss, and bone-to-implant contact</atitle><jtitle>Clinical oral implants research</jtitle><addtitle>Clin. Oral Impl. Res</addtitle><date>2015-07</date><risdate>2015</risdate><volume>26</volume><issue>7</issue><spage>753</spage><epage>760</epage><pages>753-760</pages><issn>0905-7161</issn><eissn>1600-0501</eissn><abstract>Objectives To evaluate a new hybrid drilling protocol, by the analysis of thermal changes in vitro, and their effects in the crestal bone loss and bone‐to‐implant contact in vivo. Materials and Methods Temperature changes during simulated osteotomies with a hybrid drilling technique (biologic plus simplified) (test) versus an incremental drilling technique (control) were investigated. One hundred and twenty random osteotomies were performed (60 by group) in pig ribs up to 3.75‐mm‐diameter drill to a depth of 10 mm. Thermal changes and time were recorded by paired thermocouples. In a parallel experiment, bilateral mandibular premolars P2, P3, P4, and first molar M1 were extracted from six dogs. After 2‐month healing, implant sites were randomly prepared using either of the drilling techniques. Forty eight implants of 3.75 mm diameter and 10 mm length were inserted. The dogs were euthanized at 30 and 90 days, and crestal bone loss (CBL) and bone‐to‐implant contact (BIC) were evaluated. Results The control group showed maximum temperatures of 35.3°C ± 1.8°C, ΔT of 10.4°C, and a mean time of 100 s/procedure; meanwhile, the test group showed maximum temperatures of 36.7°C ± 1.2°C, ΔT of 8.1°C, and a mean time of 240 s/procedure. After 30 days, CBL values for both groups (test: 1.168 ± 0.194 mm; control: 1.181 ± 0.113 mm) and BIC values (test: 43 ± 2.8%; control: 45 ± 1.3%) were similar, without significant differences (P &gt; 0.05). After 90 days, CBL (test: 1.173 ± 0.187 mm; control: 1.205 ± 0.122 mm) and BIC (test: 64 ± 3.3%; control: 64 ± 2.4%) values were similar, without significant differences (P &gt; 0.05). The BIC values were increased at 90 days in both groups compared with the 30‐day period (P &lt; 0.05). Conclusions Within the limitations of this study, the new hybrid protocol for the preparation of the implant bed without irrigation, increase the temperature similarly to the incremental conventional protocol, and requires twice the time for the completion of the drilling procedure in vitro. Crestal bone loss and bone‐to‐implant contact in the hybrid drilling protocol are comparable with the conventional drilling protocol and do not affect the osseointegration process in vivo.</abstract><cop>Denmark</cop><pub>Blackwell Publishing Ltd</pub><pmid>24502654</pmid><doi>10.1111/clr.12341</doi><tpages>8</tpages></addata></record>
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subjects Alveolar Process - surgery
animal studies
Animals
Bicuspid
biologic drilling
Bone healing
Bone loss
bone-to-implant contact
crestal bone loss
Dental Implantation, Endosseous - methods
Dental Implants
Dentistry
Dogs
Drilling
Healing
histomorphometry
Implants, Experimental
In vivo methods and tests
incremental drilling
Mandible - surgery
Osseointegration
Osseointegration - physiology
Osteotomy - methods
Premolars
Ribs - surgery
Swine
Temperature
Temperature requirements
Thermocouples
Transplants & implants
Wound Healing - physiology
title Novel hybrid drilling protocol: evaluation for the implant healing - thermal changes, crestal bone loss, and bone-to-implant contact
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