1,3,4-Oxadiazoles: An emerging scaffold to target growth factors, enzymes and kinases as anticancer agents

Five member heterocyclic 1,3,4-oxadiazole nucleus find unique place in medicinal chemistry and plays significant role in producing anticancer activity. The small and simple 1,3,4-oxadiazole nucleus is present in various compounds involved in research aimed at evaluating new products that posses inte...

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Veröffentlicht in:	European journal of medicinal chemistry 2015-06, Vol.97, p.124-141
Hauptverfasser:	Bajaj, Shalini, Asati, Vivek, Singh, Jagadish, Roy, Partha Pratim
Format:	Artikel
Sprache:	eng
Schlagworte:	1,3,4-Oxadiazole Anticancer Antineoplastic Agents - chemical synthesis Antineoplastic Agents - chemistry Antineoplastic Agents - therapeutic use Growth factors Humans Kinases Oxadiazoles - chemical synthesis Oxadiazoles - chemistry Oxadiazoles - therapeutic use Protein Kinases - drug effects Telomerase enzyme Vascular Endothelial Growth Factors - drug effects
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