Regulation of [Ah] gene battery enzymes and glutathione levels by 5,10-dihydroindeno[l,2-b]indole in mouse hepatoma cell lines

The murine aromatic hydrocarbon ([Ah]) gene battery consists of at least six genes that code for two functionalizing (Phase I) enzymes and four non-functionalizing (Phase II) enzymes. These enzymes are induced by compounds such as aromatic hydrocarbons and 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Carcinogenesis (New York) 1994-10, Vol.15 (10), p.2347-2352
Hauptverfasser:	Liu, R.-M., Vasiliou, V., Zhu, H., Duh, J.-L., Tabor, M.W., Puga, A., Nebert, D.W., Sainsbury, M., Shertzer, H.G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aldehyde Dehydrogenase - biosynthesis Aldehyde Dehydrogenase - genetics Animals Aryl Hydrocarbon Receptor Nuclear Translocator Biological and medical sciences Carcinogenesis, carcinogens and anticarcinogens Chemical agents Cytochrome P-450 Enzyme System - biosynthesis Cytochrome P-450 Enzyme System - genetics DNA-Binding Proteins Enzyme Induction Gene Expression Regulation, Enzymologic - drug effects Glutathione - metabolism Glutathione Transferase - biosynthesis Glutathione Transferase - genetics Indoles - pharmacology Liver Neoplasms, Experimental - enzymology Liver Neoplasms, Experimental - genetics Medical sciences Mice Mutation NAD(P)H Dehydrogenase (Quinone) - biosynthesis NAD(P)H Dehydrogenase (Quinone) - genetics Polychlorinated Dibenzodioxins - pharmacology Proteins - genetics Receptors, Aryl Hydrocarbon - genetics Receptors, Aryl Hydrocarbon - metabolism Transcription Factors Tumor Cells, Cultured - drug effects Tumors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!