Leptospirosis in a family after whitewater rafting in Thailand
Leptospirosis is a zoonosis found worldwide, with an incidence that is approximately 10 times higher in the tropics than in temperate regions. The main reservoir of leptospirosis is the rat and human infection usually results from exposure to infected animal urine or tissues. Only 10% of cases are s...
Gespeichert in:
Veröffentlicht in: | Revue médicale suisse 2015-04, Vol.11 (470), p.872-876 |
---|---|
Hauptverfasser: | , , , , , , , |
Format: | Artikel |
Sprache: | fre |
Schlagworte: | |
Online-Zugang: | Volltext |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
container_end_page | 876 |
---|---|
container_issue | 470 |
container_start_page | 872 |
container_title | Revue médicale suisse |
container_volume | 11 |
creator | Gallardo, C Williams-Smith, J Jaton, K Asner, S Cheseaux, J-J Troillet, N Manuel, O Berthod, D |
description | Leptospirosis is a zoonosis found worldwide, with an incidence that is approximately 10 times higher in the tropics than in temperate regions. The main reservoir of leptospirosis is the rat and human infection usually results from exposure to infected animal urine or tissues. Only 10% of cases are symptomatic. We present here two confirmed and two probable cases of leptospirosis in a family returning from whitewater rafting in Thailand, illustrating the wide variety of the clinical manifestations of this infection. Two of the patients were hospitalized and presented a probable Jarisch-Herxheimer reaction after initiation of beta-lactam therapy. The two others patients were treated empirically with doxycycline. We discuss here some relevant aspects of the epidemiology, clinical manifestations, therapy and the challenge of an early diagnosis of leptospirosis. |
format | Article |
fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_proquest_miscellaneous_1686999887</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1686999887</sourcerecordid><originalsourceid>FETCH-LOGICAL-p565-e62c8096806173d676cfe2e442fc925507f70ceb4b6f788caef3b81c3fcca06f3</originalsourceid><addsrcrecordid>eNo1j8tqwzAQRbVoaUKaXyhadmOQJWskbQol9AWGbrw3sjxqVPyqZBPy93VoOps7XA7DmRuyzQFYZoQyG7JP6ZutA7ngXNyRDQcmmWByS55KnOYxTSGOKSQaBmqpt33oztT6GSM9HcOMJ3tZ49qE4esCVUcbOju09-TW2y7h_po7Ur2-VIf3rPx8-zg8l9kkQWYI3GlmQK8GSrSgwHnkWBTcO8OlZMor5rApGvBKa2fRi0bnTnjnLAMvduTx7-wUx58F01z3ITnsVgUcl1TnoMEYo7Va0YcrujQ9tvUUQ2_juf5_WfwC5UNR-g</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1686999887</pqid></control><display><type>article</type><title>Leptospirosis in a family after whitewater rafting in Thailand</title><source>MEDLINE</source><source>Alma/SFX Local Collection</source><creator>Gallardo, C ; Williams-Smith, J ; Jaton, K ; Asner, S ; Cheseaux, J-J ; Troillet, N ; Manuel, O ; Berthod, D</creator><creatorcontrib>Gallardo, C ; Williams-Smith, J ; Jaton, K ; Asner, S ; Cheseaux, J-J ; Troillet, N ; Manuel, O ; Berthod, D</creatorcontrib><description>Leptospirosis is a zoonosis found worldwide, with an incidence that is approximately 10 times higher in the tropics than in temperate regions. The main reservoir of leptospirosis is the rat and human infection usually results from exposure to infected animal urine or tissues. Only 10% of cases are symptomatic. We present here two confirmed and two probable cases of leptospirosis in a family returning from whitewater rafting in Thailand, illustrating the wide variety of the clinical manifestations of this infection. Two of the patients were hospitalized and presented a probable Jarisch-Herxheimer reaction after initiation of beta-lactam therapy. The two others patients were treated empirically with doxycycline. We discuss here some relevant aspects of the epidemiology, clinical manifestations, therapy and the challenge of an early diagnosis of leptospirosis.</description><identifier>ISSN: 1660-9379</identifier><identifier>PMID: 26050305</identifier><language>fre</language><publisher>Switzerland</publisher><subject>Adolescent ; Adult ; Animals ; Anti-Bacterial Agents - adverse effects ; Anti-Bacterial Agents - therapeutic use ; beta-Lactams - adverse effects ; beta-Lactams - therapeutic use ; Doxycycline - therapeutic use ; Female ; Humans ; Leptospirosis - diagnosis ; Leptospirosis - drug therapy ; Leptospirosis - epidemiology ; Male ; Recreation ; Rivers ; Thailand - epidemiology ; Travel ; Zoonoses - diagnosis ; Zoonoses - drug therapy ; Zoonoses - epidemiology</subject><ispartof>Revue médicale suisse, 2015-04, Vol.11 (470), p.872-876</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/26050305$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Gallardo, C</creatorcontrib><creatorcontrib>Williams-Smith, J</creatorcontrib><creatorcontrib>Jaton, K</creatorcontrib><creatorcontrib>Asner, S</creatorcontrib><creatorcontrib>Cheseaux, J-J</creatorcontrib><creatorcontrib>Troillet, N</creatorcontrib><creatorcontrib>Manuel, O</creatorcontrib><creatorcontrib>Berthod, D</creatorcontrib><title>Leptospirosis in a family after whitewater rafting in Thailand</title><title>Revue médicale suisse</title><addtitle>Rev Med Suisse</addtitle><description>Leptospirosis is a zoonosis found worldwide, with an incidence that is approximately 10 times higher in the tropics than in temperate regions. The main reservoir of leptospirosis is the rat and human infection usually results from exposure to infected animal urine or tissues. Only 10% of cases are symptomatic. We present here two confirmed and two probable cases of leptospirosis in a family returning from whitewater rafting in Thailand, illustrating the wide variety of the clinical manifestations of this infection. Two of the patients were hospitalized and presented a probable Jarisch-Herxheimer reaction after initiation of beta-lactam therapy. The two others patients were treated empirically with doxycycline. We discuss here some relevant aspects of the epidemiology, clinical manifestations, therapy and the challenge of an early diagnosis of leptospirosis.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Animals</subject><subject>Anti-Bacterial Agents - adverse effects</subject><subject>Anti-Bacterial Agents - therapeutic use</subject><subject>beta-Lactams - adverse effects</subject><subject>beta-Lactams - therapeutic use</subject><subject>Doxycycline - therapeutic use</subject><subject>Female</subject><subject>Humans</subject><subject>Leptospirosis - diagnosis</subject><subject>Leptospirosis - drug therapy</subject><subject>Leptospirosis - epidemiology</subject><subject>Male</subject><subject>Recreation</subject><subject>Rivers</subject><subject>Thailand - epidemiology</subject><subject>Travel</subject><subject>Zoonoses - diagnosis</subject><subject>Zoonoses - drug therapy</subject><subject>Zoonoses - epidemiology</subject><issn>1660-9379</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo1j8tqwzAQRbVoaUKaXyhadmOQJWskbQol9AWGbrw3sjxqVPyqZBPy93VoOps7XA7DmRuyzQFYZoQyG7JP6ZutA7ngXNyRDQcmmWByS55KnOYxTSGOKSQaBmqpt33oztT6GSM9HcOMJ3tZ49qE4esCVUcbOju09-TW2y7h_po7Ur2-VIf3rPx8-zg8l9kkQWYI3GlmQK8GSrSgwHnkWBTcO8OlZMor5rApGvBKa2fRi0bnTnjnLAMvduTx7-wUx58F01z3ITnsVgUcl1TnoMEYo7Va0YcrujQ9tvUUQ2_juf5_WfwC5UNR-g</recordid><startdate>20150415</startdate><enddate>20150415</enddate><creator>Gallardo, C</creator><creator>Williams-Smith, J</creator><creator>Jaton, K</creator><creator>Asner, S</creator><creator>Cheseaux, J-J</creator><creator>Troillet, N</creator><creator>Manuel, O</creator><creator>Berthod, D</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>20150415</creationdate><title>Leptospirosis in a family after whitewater rafting in Thailand</title><author>Gallardo, C ; Williams-Smith, J ; Jaton, K ; Asner, S ; Cheseaux, J-J ; Troillet, N ; Manuel, O ; Berthod, D</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p565-e62c8096806173d676cfe2e442fc925507f70ceb4b6f788caef3b81c3fcca06f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>fre</language><creationdate>2015</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Animals</topic><topic>Anti-Bacterial Agents - adverse effects</topic><topic>Anti-Bacterial Agents - therapeutic use</topic><topic>beta-Lactams - adverse effects</topic><topic>beta-Lactams - therapeutic use</topic><topic>Doxycycline - therapeutic use</topic><topic>Female</topic><topic>Humans</topic><topic>Leptospirosis - diagnosis</topic><topic>Leptospirosis - drug therapy</topic><topic>Leptospirosis - epidemiology</topic><topic>Male</topic><topic>Recreation</topic><topic>Rivers</topic><topic>Thailand - epidemiology</topic><topic>Travel</topic><topic>Zoonoses - diagnosis</topic><topic>Zoonoses - drug therapy</topic><topic>Zoonoses - epidemiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Gallardo, C</creatorcontrib><creatorcontrib>Williams-Smith, J</creatorcontrib><creatorcontrib>Jaton, K</creatorcontrib><creatorcontrib>Asner, S</creatorcontrib><creatorcontrib>Cheseaux, J-J</creatorcontrib><creatorcontrib>Troillet, N</creatorcontrib><creatorcontrib>Manuel, O</creatorcontrib><creatorcontrib>Berthod, D</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Revue médicale suisse</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Gallardo, C</au><au>Williams-Smith, J</au><au>Jaton, K</au><au>Asner, S</au><au>Cheseaux, J-J</au><au>Troillet, N</au><au>Manuel, O</au><au>Berthod, D</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Leptospirosis in a family after whitewater rafting in Thailand</atitle><jtitle>Revue médicale suisse</jtitle><addtitle>Rev Med Suisse</addtitle><date>2015-04-15</date><risdate>2015</risdate><volume>11</volume><issue>470</issue><spage>872</spage><epage>876</epage><pages>872-876</pages><issn>1660-9379</issn><abstract>Leptospirosis is a zoonosis found worldwide, with an incidence that is approximately 10 times higher in the tropics than in temperate regions. The main reservoir of leptospirosis is the rat and human infection usually results from exposure to infected animal urine or tissues. Only 10% of cases are symptomatic. We present here two confirmed and two probable cases of leptospirosis in a family returning from whitewater rafting in Thailand, illustrating the wide variety of the clinical manifestations of this infection. Two of the patients were hospitalized and presented a probable Jarisch-Herxheimer reaction after initiation of beta-lactam therapy. The two others patients were treated empirically with doxycycline. We discuss here some relevant aspects of the epidemiology, clinical manifestations, therapy and the challenge of an early diagnosis of leptospirosis.</abstract><cop>Switzerland</cop><pmid>26050305</pmid><tpages>5</tpages></addata></record> |
fulltext | fulltext |
identifier | ISSN: 1660-9379 |
ispartof | Revue médicale suisse, 2015-04, Vol.11 (470), p.872-876 |
issn | 1660-9379 |
language | fre |
recordid | cdi_proquest_miscellaneous_1686999887 |
source | MEDLINE; Alma/SFX Local Collection |
subjects | Adolescent Adult Animals Anti-Bacterial Agents - adverse effects Anti-Bacterial Agents - therapeutic use beta-Lactams - adverse effects beta-Lactams - therapeutic use Doxycycline - therapeutic use Female Humans Leptospirosis - diagnosis Leptospirosis - drug therapy Leptospirosis - epidemiology Male Recreation Rivers Thailand - epidemiology Travel Zoonoses - diagnosis Zoonoses - drug therapy Zoonoses - epidemiology |
title | Leptospirosis in a family after whitewater rafting in Thailand |
url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-20T02%3A54%3A10IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Leptospirosis%20in%20a%20family%20after%20whitewater%20rafting%20in%20Thailand&rft.jtitle=Revue%20m%C3%A9dicale%20suisse&rft.au=Gallardo,%20C&rft.date=2015-04-15&rft.volume=11&rft.issue=470&rft.spage=872&rft.epage=876&rft.pages=872-876&rft.issn=1660-9379&rft_id=info:doi/&rft_dat=%3Cproquest_pubme%3E1686999887%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1686999887&rft_id=info:pmid/26050305&rfr_iscdi=true |