Leptospirosis in a family after whitewater rafting in Thailand

Leptospirosis is a zoonosis found worldwide, with an incidence that is approximately 10 times higher in the tropics than in temperate regions. The main reservoir of leptospirosis is the rat and human infection usually results from exposure to infected animal urine or tissues. Only 10% of cases are s...

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Veröffentlicht in:Revue médicale suisse 2015-04, Vol.11 (470), p.872-876
Hauptverfasser: Gallardo, C, Williams-Smith, J, Jaton, K, Asner, S, Cheseaux, J-J, Troillet, N, Manuel, O, Berthod, D
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container_title Revue médicale suisse
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creator Gallardo, C
Williams-Smith, J
Jaton, K
Asner, S
Cheseaux, J-J
Troillet, N
Manuel, O
Berthod, D
description Leptospirosis is a zoonosis found worldwide, with an incidence that is approximately 10 times higher in the tropics than in temperate regions. The main reservoir of leptospirosis is the rat and human infection usually results from exposure to infected animal urine or tissues. Only 10% of cases are symptomatic. We present here two confirmed and two probable cases of leptospirosis in a family returning from whitewater rafting in Thailand, illustrating the wide variety of the clinical manifestations of this infection. Two of the patients were hospitalized and presented a probable Jarisch-Herxheimer reaction after initiation of beta-lactam therapy. The two others patients were treated empirically with doxycycline. We discuss here some relevant aspects of the epidemiology, clinical manifestations, therapy and the challenge of an early diagnosis of leptospirosis.
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subjects Adolescent
Adult
Animals
Anti-Bacterial Agents - adverse effects
Anti-Bacterial Agents - therapeutic use
beta-Lactams - adverse effects
beta-Lactams - therapeutic use
Doxycycline - therapeutic use
Female
Humans
Leptospirosis - diagnosis
Leptospirosis - drug therapy
Leptospirosis - epidemiology
Male
Recreation
Rivers
Thailand - epidemiology
Travel
Zoonoses - diagnosis
Zoonoses - drug therapy
Zoonoses - epidemiology
title Leptospirosis in a family after whitewater rafting in Thailand
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