Insulin-secreting adipose-derived mesenchymal stromal cells with bone marrow–derived hematopoietic stem cells from autologous and allogenic sources for type 1 diabetes mellitus

Abstract Background aims Stem cell therapy (SCT) is now the up-coming therapeutic modality for treatment of type 1 diabetes mellitus (T1DM). Methods Our study was a prospective, open-labeled, two-armed trial for 10 T1DM patients in each arm of allogenic and autologous adipose–derived insulin-secreti...

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Veröffentlicht in:	Cytotherapy (Oxford, England) England), 2015-07, Vol.17 (7), p.940-947
Hauptverfasser:	Thakkar, Umang G, Trivedi, Hargovind L, Vanikar, Aruna V, Dave, Shruti D
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipose Tissue - cytology Adult Advanced Basic Science Blood Glucose - metabolism Bone Marrow Cells - cytology C-peptide C-Peptide - blood Cell- and Tissue-Based Therapy - methods Diabetes Mellitus, Type 1 - therapy Female Glycated Hemoglobin A - analysis glycosylated hemoglobin Hematopoietic Stem Cell Transplantation Hematopoietic Stem Cells - cytology Hematopoietic Stem Cells - metabolism Humans Insulin - metabolism insulin requirement Insulin Secretion insulin-secreting cells Leukocyte Common Antigens - blood Male Mesenchymal Stem Cell Transplantation Mesenchymal Stem Cells - cytology Mesenchymal Stem Cells - metabolism mesenchymal stromal cells Obesity - therapy Other Prospective Studies stem cell therapy Subcutaneous Fat - metabolism type 1 diabetes mellitus Young Adult
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