Plasmalogen phospholipids protect internodal myelin from oxidative damage

Reactive oxygen species (ROS) are implicated in a range of degenerative conditions, including aging, neurodegenerative diseases, and neurological disorders. Myelin is a lipid-rich multilamellar sheath that facilitates rapid nerve conduction in vertebrates. Given the high energetic demands and low an...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Free radical biology & medicine 2015-07, Vol.84, p.296-310
Hauptverfasser:	Luoma, Adrienne M., Kuo, Fonghsu, Cakici, Ozgur, Crowther, Michelle N., Denninger, Andrew R., Avila, Robin L., Brites, Pedro, Kirschner, Daniel A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Ascorbate Chelating Agents - pharmacology Drug Evaluation, Preclinical Edetic Acid - pharmacology Formates - pharmacology Free Radical Scavengers - pharmacology Membranes Mice, Knockout Myelin Myelin Sheath - drug effects Myelin Sheath - metabolism Optic nerve Optic Nerve - metabolism Optic Nerve - pathology Oxidation-Reduction Oxidative damage Oxidative Stress Peroxisomal Targeting Signal 2 Receptor Plasmalogen lipids Plasmalogens - pharmacology Protein Carbonylation Reactive Oxygen Species - metabolism Receptors, Cytoplasmic and Nuclear - genetics Sciatic nerve Sciatic Nerve - metabolism Sciatic Nerve - pathology X-ray diffraction
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!