Altered Left Ventricular Twist Is Associated with Clinical Severity in Adults and Adolescents with Homozygous Sickle Cell Anemia

Background Sickle cell anemia (SCA) is associated with cardiac abnormalities and premature death. The aims of this study were to identify early markers of cardiac dysfunction through ventricular strain and ventricular twist and determine the relationships between these measures and other markers of...

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Veröffentlicht in:	Journal of the American Society of Echocardiography 2015-06, Vol.28 (6), p.692-699
Hauptverfasser:	Braga, Joao Carlos Moron Saes, MD, PhD, Assef, Jorge Eduardo, MD, PhD, Waib, Paulo Henrique, MD, PhD, de Sousa, Amanda Guerra de Moraes Rego, MD, PhD, de Mattos Barretto, Rodrigo Bellio, MD, PhD, Guimarães Filho, Fábio Villaça, MD, PhD, Rodrigues, Alexandre, MD, PhD, Vilela, Fernanda Di Tullio Trindade, MD, de Castro Bienert, Igor Ribeiro, MD, Tan, Doralice Marvulle, MD, Peluccio, Danielen Cristina Mariano
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Anemia, Sickle Cell - complications Anemia, Sickle Cell - diagnosis Cardiovascular Echocardiography - methods Female Heart Ventricles - diagnostic imaging Humans Left ventricular twist Male Reproducibility of Results Sensitivity and Specificity Severity of Illness Index Sickle cell anemia Speckle-tracking echocardiography Torsion Abnormality - diagnostic imaging Torsion Abnormality - etiology Ventricular Dysfunction, Left - diagnostic imaging Ventricular Dysfunction, Left - etiology
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