Principles Underlying Dose Selection for, and Extrapolation from, the Carcinogen Bioassay: Dose Influences Mechanism

The purpose of the bioassay is not to simply find chemicals that can be labeled as carcinogens. On the contrary, the overall goal is to provide a reasonable assessment of the possible hazard that a chemical might pose to people under realistic conditions of exposure. This paper focuses upon the dose...

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Veröffentlicht in:	Regulatory toxicology and pharmacology 1995-06, Vol.21 (3), p.418-421
Hauptverfasser:	Counts, J.L., Goodman, J.I.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Carcinogenesis, carcinogens and anticarcinogens Carcinogenicity Tests - methods Carcinogens - toxicity Chemical agents Dose-Response Relationship, Drug Medical sciences Models, Biological Tumors
Online-Zugang:	Volltext
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