Long-term observational study of afamelanotide in 115 patients with erythropoietic protoporphyria

Summary Background In erythropoietic protoporphyria (EPP), an inherited disease of porphyrin‐biosynthesis, the accumulation of protoporphyrin in the skin causes severely painful phototoxic reactions. Symptom prevention was impossible until recently when afamelanotide became available. Afamelanotide‐...

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Veröffentlicht in:	British journal of dermatology (1951) 2015-06, Vol.172 (6), p.1601-1612
Hauptverfasser:	Biolcati, G., Marchesini, E., Sorge, F., Barbieri, L., Schneider-Yin, X., Minder, E.I.
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Cutaneous Adult alpha-MSH - administration & dosage alpha-MSH - adverse effects alpha-MSH - analogs & derivatives Delayed-Action Preparations Dermatologic Agents - administration & dosage Dermatologic Agents - adverse effects Erythropoietic protoporphyria Female Hereditary diseases Humans Long-Term Care Male Medication Adherence Melanins - metabolism Nausea Observational studies Patients Porphyria Pregnancy Protoporphyria, Erythropoietic - drug therapy Protoporphyrin Quality of Life Retrospective Studies Skin pigmentation Treatment Outcome
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