A novel literature-based approach to identify genetic and molecular predictors of survival in glioblastoma multiforme: Analysis of 14,678 patients using systematic review and meta-analytical tools

Abstract Glioblastoma multiforme (GBM) has a poor prognosis despite maximal multimodal therapy. Biomarkers of relevance to prognosis which may also identify treatment targets are needed. A few hundred genetic and molecular predictors have been implicated in the literature, however with the exception...

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Veröffentlicht in:	Journal of clinical neuroscience 2015-05, Vol.22 (5), p.785-799
Hauptverfasser:	Thuy, Matthew N.T, Kam, Jeremy K.T, Lee, Geoffrey C.Y, Tao, Peter L, Ling, Dorothy Q, Cheng, Melissa, Goh, Su Kah, Papachristos, Alexander J, Shukla, Lipi, Wall, Krystal-Leigh, Smoll, Nicolas R, Jones, Jordan J, Gikenye, Njeri, Soh, Bob, Moffat, Brad, Johnson, Nick, Drummond, Katharine J
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Adults Biomarkers Brain Neoplasms - diagnosis Brain Neoplasms - genetics Brain Neoplasms - mortality Female Genetic Markers - genetics Glioblastoma Glioblastoma - diagnosis Glioblastoma - genetics Glioblastoma - mortality Humans Male Meta-analysis Middle Aged Mutation - genetics Neurology Neurosurgery Predictive Value of Tests Prognosis Survival Survival Rate - trends Systematic review
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