Construction of antibody-like nanoparticles for selective protein sequestration in living cells

We demonstrate the successful construction of fluorescently labeled magnetic antibody-like nanoparticles (ANPs) via a facile one-step surface-initiated in situ molecular imprinting approach over silica coated magnetite (Fe3O4@SiO2) core-shell nanocomposites. The as-prepared ANPs had a highly compact...

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Veröffentlicht in:	Nanoscale 2015-04, Vol.7 (16), p.7162-7167
Hauptverfasser:	Liu, Yibin, Fang, Simin, Zhai, Junqiu, Zhao, Meiping
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies - chemistry Antibodies - metabolism Carbocyanines - chemistry Cell Survival - drug effects Construction Deoxyribonuclease I - chemistry Deoxyribonuclease I - metabolism Dispersions Ferrosoferric Oxide - chemistry HeLa Cells Humans Magnetic Fields Magnetite Magnetite Nanoparticles - chemistry Magnetite Nanoparticles - toxicity Microscopy, Fluorescence Molecular Imprinting Nanocomposites Nanoparticles Nanostructure Particle Size Proteins Rhodamines - chemistry Silicon Dioxide - chemistry Spectrometry, Fluorescence Surface Properties Target tracking
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