Erythrocyte polyunsaturated fatty acid levels in young people at ultra-high risk for psychotic disorder and healthy adolescent controls

Erythrocyte polyunsaturated fatty acid levels in young people at ultra-high risk for psychotic disorder and healthy adolescent controls

Abstract Erythrocyte polyunsaturated fatty acid (PUFA) levels from individuals at ultra-high risk (UHR) for psychosis ( n =80) were compared to existing data from healthy controls ( n =142). Results demonstrated PUFA deficits (α-linolenic acid, eicosapentanoic acid, all ω-6 PUFAs) for the UHR group....

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Veröffentlicht in:Psychiatry research 2015-07, Vol.228 (1), p.174-176
Hauptverfasser: Rice, Simon M, Schäfer, Miriam R, Klier, Claudia, Mossaheb, Nilufar, Vijayakumar, Nandita, Amminger, Günter Paul
Format: Artikel
Sprache:eng
Schlagworte:
Adolescent
Adult
Erythrocytes - metabolism
Fatty Acids, Omega-3 - blood
Fatty Acids, Omega-6 - blood
Female
Humans
Male
Polyunsaturated fatty acids
Psychiatry
Psychosis
Psychotic Disorders - blood
Risk
Ultra-high risk
Young Adult
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Zusammenfassung:Abstract Erythrocyte polyunsaturated fatty acid (PUFA) levels from individuals at ultra-high risk (UHR) for psychosis ( n =80) were compared to existing data from healthy controls ( n =142). Results demonstrated PUFA deficits (α-linolenic acid, eicosapentanoic acid, all ω-6 PUFAs) for the UHR group. Findings provide a rationale for PUFA based interventions in emerging psychosis.
ISSN:0165-1781
1872-7123
DOI:10.1016/j.psychres.2015.04.036