Noninvasive Visualization of Tumoral Fibrin Deposition Using a Peptidic Fibrin-Binding Single Photon Emission Computed Tomography Tracer

Fibrin deposition plays an important role in the formation of mature tumor stroma and provides a facilitating scaffold for tumor angiogenesis. This study investigates the potential of the 111In-labeled fibrin-binding peptide EPep for SPECT imaging of intratumoral fibrin deposition. 111In-EPep and ne...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Molecular pharmaceutics 2015-06, Vol.12 (6), p.1921-1928
Hauptverfasser:	Starmans, Lucas W. E, van Mourik, Tiemen, Rossin, Raffaella, Verel, Iris, Nicolay, Klaas, Grüll, Holger
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Line, Tumor Female Fibrin - metabolism Humans Mice Mice, Inbred BALB C Neoplasms - diagnosis Neoplasms - diagnostic imaging Peptides - metabolism Radiography Tomography, Emission-Computed, Single-Photon - methods
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!