Peripheral T lymphocyte depletion by apoptosis after CD4 ligation in vivo: Selective loss of CD44 super(-) and 'activating' memory T cells

We have demonstrated that a single intravenous bolus of rat anti-CD4 MoAb caused a small but prolonged increase in apoptosis in murine lymph nodes. We have quantified this process using the novel Highly Optimized Microscope Environment (HOME) interactive image analysis system and shown that the incr...

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Veröffentlicht in:Clinical and experimental immunology 1994-01, Vol.95 (1), p.195-200
Hauptverfasser: Howie, SEM, Sommerfield, A J, Gray, E, Harrison, D J
Format: Artikel
Sprache:eng
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