Automated metaphase finding: an assessment of the efficiency of the METAFER2 system in a routine mutagenicity assay

The efficiency of the automated metaphase finding system METAFER2 is assessed in a routine mutagenicity assay using an aneuploid rat liver cell line treated with various promutagens. Data sets generated by automated and manual selection of metaphases are compared. It is demonstrated that METAFER2 ro...

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Veröffentlicht in:	Mutation Research 1995-02, Vol.334 (1), p.97-102
Hauptverfasser:	Huber, R., Kulka, U., Lörch, Th, Braselmann, H., Bauchinger, M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aneuploidy Animals Automated metaphase finding Automation Biological and medical sciences Cell Line Chemical mutagenesis Chromosome Aberrations Evaluation Studies as Topic Image analysis Image Processing, Computer-Assisted Medical sciences METAFER2 Metaphase Mutagenicity Tests - methods Mutagens - toxicity Rats Sister Chromatid Exchange Time Factors Toxicology
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