N‐Benzylcinnamide induces apoptosis in HPV16 and HPV18 cervical cancer cells via suppression of E6 and E7 protein expression

Seventy percent of all cervical cancers are caused by human papillomavirus (HPV) infections. Natural products are being extensively explored for their potential ability to prevent and treat cervical cancers. N‐benzylcinnamide (PT‐3) is a natural product purified from Piper submultinerve. Whether or...

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Veröffentlicht in:	IUBMB life 2015-05, Vol.67 (5), p.374-379
Hauptverfasser:	Xiong, Yuanhuan, Chen, Lin, Luo, Puying
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Apoptosis - drug effects Cervical cancer cervical cancers Cinnamates - pharmacology DNA-Binding Proteins - metabolism E7 protein Female HeLa Cells Human papillomavirus Humans Natural products N‐benzylcinnamide Oncogene Proteins, Viral - metabolism p53 Protein Papillomavirus E7 Proteins - metabolism Repressor Proteins - metabolism Uterine Cervical Neoplasms - metabolism Uterine Cervical Neoplasms - pathology
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