The importance of extracellular matrix for cell function and in vivo likeness

Fibrotic diseases may be described as a disease of the extracellular matrix, where the balance between matrix formation and degradation has been shifted leading to an accumulation of matrix. Currently a fit for purpose model and readily available approach are adapted when doing cell cultures, which...

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Veröffentlicht in:Experimental and molecular pathology 2015-04, Vol.98 (2), p.286-294
Hauptverfasser: Hansen, N.U.B., Genovese, F., Leeming, D.J., Karsdal, M.A.
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Sprache:eng
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