Topical cyclodextrin reduces amyloid beta and inflammation improving retinal function in ageing mice

Retinal ageing results in chronic inflammation, extracellular deposition, including that of amyloid beta (Aβ) and declining visual function. In humans this can progress into age-related macular degeneration (AMD), which is without cure. Therapeutic approaches have focused on systemic immunotherapies...

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Veröffentlicht in:Experimental eye research 2015-06, Vol.135, p.59-66
Hauptverfasser: Hoh Kam, Jaimie, Lynch, Aisling, Begum, Rana, Cunea, Alex, Jeffery, Glen
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Sprache:eng
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