Effect of mucoadhesive polymers on the in vitro performance of insulin-loaded silica nanoparticles: Interactions with mucin and biomembrane models

[Display omitted] The present paper focuses on the development and characterization of silica nanoparticles (SiNP) coated with hydrophilic polymers as mucoadhesive carriers for oral administration of insulin. SiNP were prepared by sol–gel technology under mild conditions and coated with different hy...

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Veröffentlicht in:European journal of pharmaceutics and biopharmaceutics 2015-06, Vol.93, p.118-126
Hauptverfasser: Andreani, Tatiana, Miziara, Leonardo, Lorenzón, Esteban N., de Souza, Ana Luiza R., Kiill, Charlene P., Fangueiro, Joana F., Garcia, Maria L., Gremião, Palmira D., Silva, Amélia M., Souto, Eliana B.
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Sprache:eng
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