Prognostic Factors for Outcome in Pediatric Probable Lesional Frontal Lobe Epilepsy With an Unknown Cause (Cryptogenic)
The outcomes of children with cryptogenic seizures most probably arising from the frontal lobe are difficult to predict. We retrospectively collected data on 865 pediatric patients with epilepsy. In 78 patients with cryptogenic frontal lobe epilepsy, the age at first seizure was inversely correlated...
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| Veröffentlicht in: | Journal of child neurology 2014-12, Vol.29 (12), p.1660-1663 |
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| container_title | Journal of child neurology |
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| creator | Lee, Inn-Chi Chen, Yung-Jung Lee, Hong-Shen Li, Shuan-Yow |
| description | The outcomes of children with cryptogenic seizures most probably arising from the frontal lobe are difficult to predict. We retrospectively collected data on 865 pediatric patients with epilepsy. In 78 patients with cryptogenic frontal lobe epilepsy, the age at first seizure was inversely correlated with the outcome, including the degree of intellectual disability/developmental delay (P = .002) and seizure frequency (P = .02) after adequate treatment. Intellectual disability was more prevalent in children with a first seizure at 0 to 3 years old (P = .002), and seizures were more frequent in those with a first seizure at 0 to 6 years old than at 7 to 16 years old (P = .026). For pediatric cryptogenic frontal lobe epilepsy, the age at first seizure is important and inversely correlated with outcome, including seizure frequency and intellectual disability. |
| doi_str_mv | 10.1177/0883073813511855 |
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We retrospectively collected data on 865 pediatric patients with epilepsy. In 78 patients with cryptogenic frontal lobe epilepsy, the age at first seizure was inversely correlated with the outcome, including the degree of intellectual disability/developmental delay (P = .002) and seizure frequency (P = .02) after adequate treatment. Intellectual disability was more prevalent in children with a first seizure at 0 to 3 years old (P = .002), and seizures were more frequent in those with a first seizure at 0 to 6 years old than at 7 to 16 years old (P = .026). For pediatric cryptogenic frontal lobe epilepsy, the age at first seizure is important and inversely correlated with outcome, including seizure frequency and intellectual disability.</description><identifier>ISSN: 0883-0738</identifier><identifier>EISSN: 1708-8283</identifier><identifier>DOI: 10.1177/0883073813511855</identifier><identifier>PMID: 24352160</identifier><language>eng</language><publisher>Los Angeles, CA: SAGE Publications</publisher><subject>Adolescent ; Analysis of Variance ; Child ; Child, Preschool ; Developmental Disabilities - etiology ; Electroencephalography ; Epilepsy, Frontal Lobe - complications ; Epilepsy, Frontal Lobe - diagnosis ; Epilepsy, Frontal Lobe - psychology ; Female ; Humans ; Infant ; Intellectual Disability - diagnosis ; Intellectual Disability - etiology ; Male ; Pediatrics ; Prognosis ; Regression Analysis ; Retrospective Studies</subject><ispartof>Journal of child neurology, 2014-12, Vol.29 (12), p.1660-1663</ispartof><rights>The Author(s) 2013</rights><rights>The Author(s) 2013.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c370t-305f0720801be7fb4c4fe4c7b43f713d8ca80f0f45537281dad8d67a9676c2423</citedby><cites>FETCH-LOGICAL-c370t-305f0720801be7fb4c4fe4c7b43f713d8ca80f0f45537281dad8d67a9676c2423</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://journals.sagepub.com/doi/pdf/10.1177/0883073813511855$$EPDF$$P50$$Gsage$$H</linktopdf><linktohtml>$$Uhttps://journals.sagepub.com/doi/10.1177/0883073813511855$$EHTML$$P50$$Gsage$$H</linktohtml><link.rule.ids>314,780,784,21819,27924,27925,43621,43622</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24352160$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Lee, Inn-Chi</creatorcontrib><creatorcontrib>Chen, Yung-Jung</creatorcontrib><creatorcontrib>Lee, Hong-Shen</creatorcontrib><creatorcontrib>Li, Shuan-Yow</creatorcontrib><title>Prognostic Factors for Outcome in Pediatric Probable Lesional Frontal Lobe Epilepsy With an Unknown Cause (Cryptogenic)</title><title>Journal of child neurology</title><addtitle>J Child Neurol</addtitle><description>The outcomes of children with cryptogenic seizures most probably arising from the frontal lobe are difficult to predict. We retrospectively collected data on 865 pediatric patients with epilepsy. In 78 patients with cryptogenic frontal lobe epilepsy, the age at first seizure was inversely correlated with the outcome, including the degree of intellectual disability/developmental delay (P = .002) and seizure frequency (P = .02) after adequate treatment. Intellectual disability was more prevalent in children with a first seizure at 0 to 3 years old (P = .002), and seizures were more frequent in those with a first seizure at 0 to 6 years old than at 7 to 16 years old (P = .026). For pediatric cryptogenic frontal lobe epilepsy, the age at first seizure is important and inversely correlated with outcome, including seizure frequency and intellectual disability.</description><subject>Adolescent</subject><subject>Analysis of Variance</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Developmental Disabilities - etiology</subject><subject>Electroencephalography</subject><subject>Epilepsy, Frontal Lobe - complications</subject><subject>Epilepsy, Frontal Lobe - diagnosis</subject><subject>Epilepsy, Frontal Lobe - psychology</subject><subject>Female</subject><subject>Humans</subject><subject>Infant</subject><subject>Intellectual Disability - diagnosis</subject><subject>Intellectual Disability - etiology</subject><subject>Male</subject><subject>Pediatrics</subject><subject>Prognosis</subject><subject>Regression Analysis</subject><subject>Retrospective Studies</subject><issn>0883-0738</issn><issn>1708-8283</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqN0TFv2zAQBWCiaNE4afdOAcdkUHsUSZEeCyNOChhIhgQZBYo6ukxlUiEpBP73keG0Q4ECnW64795wj5AvDL4yptQ30JqD4ppxyZiW8h1ZMAW60rXm78nisK4O-xNymvMTAGi5hI_kpBZc1qyBBXm5S3EbYi7e0rWxJaZMXUz0dio27pD6QO-w96akGcy2M92AdIPZx2AGuk4xlHluYof0avQDjnlPH335SU2gD-FXiC-BrsyUkV6s0n4scYvB28tP5IMzQ8bPb_OMPKyv7lc31eb2-sfq-6ayXEGpOEgHqgYNrEPlOmGFQ2FVJ7hTjPfaGg0OnJCSq1qz3vS6b5RZNqqxtaj5Gbk45o4pPk-YS7vz2eIwmIBxyi1rNOdiyYX8D1rPUEoGM4UjtSnmnNC1Y_I7k_Ytg_bQTPt3M_PJ-Vv61O2w_3Pwu4oZVEeQzRbbpzil-cH534GvGhCVDA</recordid><startdate>201412</startdate><enddate>201412</enddate><creator>Lee, Inn-Chi</creator><creator>Chen, Yung-Jung</creator><creator>Lee, Hong-Shen</creator><creator>Li, Shuan-Yow</creator><general>SAGE Publications</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>7TK</scope></search><sort><creationdate>201412</creationdate><title>Prognostic Factors for Outcome in Pediatric Probable Lesional Frontal Lobe Epilepsy With an Unknown Cause (Cryptogenic)</title><author>Lee, Inn-Chi ; Chen, Yung-Jung ; Lee, Hong-Shen ; Li, Shuan-Yow</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c370t-305f0720801be7fb4c4fe4c7b43f713d8ca80f0f45537281dad8d67a9676c2423</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Adolescent</topic><topic>Analysis of Variance</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>Developmental Disabilities - etiology</topic><topic>Electroencephalography</topic><topic>Epilepsy, Frontal Lobe - complications</topic><topic>Epilepsy, Frontal Lobe - diagnosis</topic><topic>Epilepsy, Frontal Lobe - psychology</topic><topic>Female</topic><topic>Humans</topic><topic>Infant</topic><topic>Intellectual Disability - diagnosis</topic><topic>Intellectual Disability - etiology</topic><topic>Male</topic><topic>Pediatrics</topic><topic>Prognosis</topic><topic>Regression Analysis</topic><topic>Retrospective Studies</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Lee, Inn-Chi</creatorcontrib><creatorcontrib>Chen, Yung-Jung</creatorcontrib><creatorcontrib>Lee, Hong-Shen</creatorcontrib><creatorcontrib>Li, Shuan-Yow</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>Neurosciences Abstracts</collection><jtitle>Journal of child neurology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Lee, Inn-Chi</au><au>Chen, Yung-Jung</au><au>Lee, Hong-Shen</au><au>Li, Shuan-Yow</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Prognostic Factors for Outcome in Pediatric Probable Lesional Frontal Lobe Epilepsy With an Unknown Cause (Cryptogenic)</atitle><jtitle>Journal of child neurology</jtitle><addtitle>J Child Neurol</addtitle><date>2014-12</date><risdate>2014</risdate><volume>29</volume><issue>12</issue><spage>1660</spage><epage>1663</epage><pages>1660-1663</pages><issn>0883-0738</issn><eissn>1708-8283</eissn><abstract>The outcomes of children with cryptogenic seizures most probably arising from the frontal lobe are difficult to predict. We retrospectively collected data on 865 pediatric patients with epilepsy. In 78 patients with cryptogenic frontal lobe epilepsy, the age at first seizure was inversely correlated with the outcome, including the degree of intellectual disability/developmental delay (P = .002) and seizure frequency (P = .02) after adequate treatment. Intellectual disability was more prevalent in children with a first seizure at 0 to 3 years old (P = .002), and seizures were more frequent in those with a first seizure at 0 to 6 years old than at 7 to 16 years old (P = .026). For pediatric cryptogenic frontal lobe epilepsy, the age at first seizure is important and inversely correlated with outcome, including seizure frequency and intellectual disability.</abstract><cop>Los Angeles, CA</cop><pub>SAGE Publications</pub><pmid>24352160</pmid><doi>10.1177/0883073813511855</doi><tpages>4</tpages></addata></record> |
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| subjects | Adolescent Analysis of Variance Child Child, Preschool Developmental Disabilities - etiology Electroencephalography Epilepsy, Frontal Lobe - complications Epilepsy, Frontal Lobe - diagnosis Epilepsy, Frontal Lobe - psychology Female Humans Infant Intellectual Disability - diagnosis Intellectual Disability - etiology Male Pediatrics Prognosis Regression Analysis Retrospective Studies |
| title | Prognostic Factors for Outcome in Pediatric Probable Lesional Frontal Lobe Epilepsy With an Unknown Cause (Cryptogenic) |
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