Temperature controls oxidative phosphorylation and reactive oxygen species production through uncoupling in rat skeletal muscle mitochondria

Mitochondrial respiratory and phosphorylation activities, mitochondrial uncoupling, and hydrogen peroxide formation were studied in isolated rat skeletal muscle mitochondria during experimentally induced hypothermia (25°C) and hyperthermia (42°C) compared to the physiological temperature of resting...

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Veröffentlicht in:	Free radical biology & medicine 2015-06, Vol.83, p.12-20
Hauptverfasser:	Jarmuszkiewicz, Wieslawa, Woyda-Ploszczyca, Andrzej, Koziel, Agnieszka, Majerczak, Joanna, Zoladz, Jerzy A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Citrate (si)-Synthase - metabolism Electron Transport Complex IV - metabolism Fever - physiopathology Free radicals Hydrogen Peroxide - metabolism Hypothermia - physiopathology Male Membrane Potential, Mitochondrial Mitochondria, Muscle - metabolism Mitochondrial function Mitochondrial Proteins - metabolism Muscle, Skeletal - metabolism Oxidation-Reduction Oxidative Phosphorylation Oxidative Stress Oxygen Consumption Rats Rats, Wistar Reactive Oxygen Species - metabolism Skeletal muscle mitochondria Temperature Uncoupling protein
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