Exogenous tyrosol inhibits planktonic cells and biofilms of Candida species and enhances their susceptibility to antifungals

Tyrosol is a quorum-sensing molecule of Candida albicans able to induce hyphal development in the early and intermediate stages of biofilm growth. In the present study, we evaluated the effect of high concentrations of exogenous tyrosol on planktonic cells and biofilms of C. albicans (n = 10) and C....

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Veröffentlicht in:	FEMS yeast research 2015-06, Vol.15 (4), p.fov012-fov012
Hauptverfasser:	Cordeiro, Rossana de A., Teixeira, Carlos E.C., Brilhante, Raimunda S.N., Castelo-Branco, Débora S.C.M., Alencar, Lucas P., de Oliveira, Jonathas S., Monteiro, André J., Bandeira, Tereza J.P.G., Sidrim, José J.C., Moreira, José Luciano Bezerra, Rocha, Marcos F.G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amphotericin B Amphotericin B - metabolism Antifungal agents Antifungal Agents - metabolism Azoles Biofilms Biofilms - drug effects Candida Candida - drug effects Candida - physiology Candida albicans Drug interaction Drug Synergism Ergosterol Fluconazole Fluconazole - metabolism Itraconazole Itraconazole - metabolism Microbial Sensitivity Tests Minimum inhibitory concentration Phenylethyl Alcohol - analogs & derivatives Phenylethyl Alcohol - metabolism Planktonic cells Species Tyrosol
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