Identification of the metabolites of TCM prescription Sinisan, found in miniature pig urine via intragastric administration

•The metabolic profile of pulverized Sinisan was studied in miniature pig.•Fifty compounds from urine were identified by HPLC–HRMS–SPE-TT–NMR.•Ten unchanged parent glycosides were found as major but not reported in rat.•Most of phase II metabolites are glucuronides instead of sulfates in rat.•Struct...

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