Long-term outcomes of granulocyte colony-stimulating factor-combined conditioning in allogeneic hematopoietic stem cell transplantation from HLA-identical family donors for myeloid malignancies
Highlights • We retrospectively analyzed the long-term outcomes of allogeneic BMT/PBSCT after conditioning consisting of 12 Gy TBI and G-CSF-combined high-dose Ara-C of 24 g/m2 in 89 adult patients with myeloid malignancies in our institute. • The probability of overall survival and cumulative incid...
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Veröffentlicht in: | Leukemia research 2015-06, Vol.39 (6), p.625-631 |
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Hauptverfasser: | , , , , , , |
Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | Highlights • We retrospectively analyzed the long-term outcomes of allogeneic BMT/PBSCT after conditioning consisting of 12 Gy TBI and G-CSF-combined high-dose Ara-C of 24 g/m2 in 89 adult patients with myeloid malignancies in our institute. • The probability of overall survival and cumulative incidence of relapse at 10 years were 64.5% and 22.2%, respectively. • Disease status at HSCT was associated with survival and relapse. • G-CSF-combined regimen provides long-term remission in patients with myeloid malignancies. |
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ISSN: | 0145-2126 1873-5835 |
DOI: | 10.1016/j.leukres.2015.03.022 |