Objective and subjective image quality of primary and recurrent squamous cell carcinoma on head and neck low-tube-voltage 80-kVp computed tomography
Introduction To investigate low-tube-voltage 80-kVp computed tomography (CT) of head and neck primary and recurrent squamous cell carcinoma (SCC) regarding objective and subjective image quality. Methods We retrospectively evaluated 65 patients (47 male, 18 female; mean age: 62.1 years) who underwen...
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| Veröffentlicht in: | Neuroradiology 2015-06, Vol.57 (6), p.645-651 |
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| creator | Scholtz, Jan-Erik Kaup, Moritz Kraft, Johannes Nöske, Eva-Maria Scheerer, Friedrich Schulz, Boris Burck, Iris Wagenblast, Jens Kerl, J. Matthias Bauer, Ralf W. Lehnert, Thomas Vogl, Thomas J. Wichmann, Julian L. |
| description | Introduction
To investigate low-tube-voltage 80-kVp computed tomography (CT) of head and neck primary and recurrent squamous cell carcinoma (SCC) regarding objective and subjective image quality.
Methods
We retrospectively evaluated 65 patients (47 male, 18 female; mean age: 62.1 years) who underwent head and neck dual-energy CT (DECT) due to biopsy-proven primary (
n
= 50) or recurrent (
n
= 15) SCC. Eighty peak kilovoltage and standard blended 120-kVp images were compared. Attenuation and noise of malignancy and various soft tissue structures were measured. Tumor signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) were calculated. Subjective image quality was rated by three reviewers using 5-point grading scales regarding overall image quality, lesion delineation, image sharpness, and image noise. Radiation dose was assessed as CT dose index volume (CTDI
vol
). Interobserver agreement was calculated using intraclass correlation coefficient (ICC).
Results
Mean tumor attenuation (153.8 Hounsfield unit (HU) vs. 97.1 HU), SNR (10.7 vs. 8.3), CNR (8.1 vs. 4.8), and subjective tumor delineation (score, 4.46 vs. 4.13) were significantly increased (all
P
|
| doi_str_mv | 10.1007/s00234-015-1512-x |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1682428112</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>3688967191</sourcerecordid><originalsourceid>FETCH-LOGICAL-c549t-4d325c21cd80c4d0cedb72ae690486cd43b1dc52cc809375e646ccf295542bff3</originalsourceid><addsrcrecordid>eNp1kc9u1DAQhy0EokvhAbggS1x6MdiOnThHVPFPqtQLcLWc8WSbbRKndtJ236MPjNNdKoTEybLnm589_gh5K_gHwXn1MXEuC8W40ExoIdn9M7IRqpBM1JI_J5tcNqyoFT8hr1Lacc6LqqhekhOpDTdCyg15uGx2CHN3i9SNnqbladsNbov0ZnF9N-9paOkU81HcP3IRYYkRx5mmTAxhSRSw7ym4CN0YBkfDSK_Q-Ud6RLimfbhj89Iguw39vEYbzq5_TRTCMC0zejqHIWyjm672r8mL1vUJ3xzXU_Lzy-cf59_YxeXX7-efLhhoVc9M-UJqkAK84aA8B_RNJR2WNVemBK-KRnjQEsDwuqg0lqoEaGWttZJN2xan5OyQO8Vws2Ca7dCldQ43Yh7JitJIJY0QMqPv_0F3YYljft1KCaPqSulMiQMFMaQUsbXHT7OC21WZPSizWZldldn73PPumLw0A_qnjj-OMiAPQMqlcYvxr6v_m_obigWj5A</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1681849745</pqid></control><display><type>article</type><title>Objective and subjective image quality of primary and recurrent squamous cell carcinoma on head and neck low-tube-voltage 80-kVp computed tomography</title><source>MEDLINE</source><source>SpringerLink Journals - AutoHoldings</source><creator>Scholtz, Jan-Erik ; Kaup, Moritz ; Kraft, Johannes ; Nöske, Eva-Maria ; Scheerer, Friedrich ; Schulz, Boris ; Burck, Iris ; Wagenblast, Jens ; Kerl, J. Matthias ; Bauer, Ralf W. ; Lehnert, Thomas ; Vogl, Thomas J. ; Wichmann, Julian L.</creator><creatorcontrib>Scholtz, Jan-Erik ; Kaup, Moritz ; Kraft, Johannes ; Nöske, Eva-Maria ; Scheerer, Friedrich ; Schulz, Boris ; Burck, Iris ; Wagenblast, Jens ; Kerl, J. Matthias ; Bauer, Ralf W. ; Lehnert, Thomas ; Vogl, Thomas J. ; Wichmann, Julian L.</creatorcontrib><description>Introduction
To investigate low-tube-voltage 80-kVp computed tomography (CT) of head and neck primary and recurrent squamous cell carcinoma (SCC) regarding objective and subjective image quality.
Methods
We retrospectively evaluated 65 patients (47 male, 18 female; mean age: 62.1 years) who underwent head and neck dual-energy CT (DECT) due to biopsy-proven primary (
n
= 50) or recurrent (
n
= 15) SCC. Eighty peak kilovoltage and standard blended 120-kVp images were compared. Attenuation and noise of malignancy and various soft tissue structures were measured. Tumor signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) were calculated. Subjective image quality was rated by three reviewers using 5-point grading scales regarding overall image quality, lesion delineation, image sharpness, and image noise. Radiation dose was assessed as CT dose index volume (CTDI
vol
). Interobserver agreement was calculated using intraclass correlation coefficient (ICC).
Results
Mean tumor attenuation (153.8 Hounsfield unit (HU) vs. 97.1 HU), SNR (10.7 vs. 8.3), CNR (8.1 vs. 4.8), and subjective tumor delineation (score, 4.46 vs. 4.13) were significantly increased (all
P
< 0.001) with 80-kVp acquisition compared to standard blended 120-kVp images. Noise of all measured structures was increased in 80-kVp acquisition (
P
< 0.001). Overall interobserver agreement was good (ICC, 0.86; 95 % confidence intervals: 0.82–0.89). CTDI
vol
was reduced by 48.7 % with 80-kVp acquisition compared to standard DECT (4.85 ± 0.51 vs. 9.94 ± 0.81 mGy cm,
P
< 0.001).
Conclusions
Head and neck CT with low-tube-voltage 80-kVp acquisition provides increased tumor delineation, SNR, and CNR for CT imaging of primary and recurrent SCC compared to standard 120-kVp acquisition with an accompanying significant reduction of radiation exposure.</description><identifier>ISSN: 0028-3940</identifier><identifier>EISSN: 1432-1920</identifier><identifier>DOI: 10.1007/s00234-015-1512-x</identifier><identifier>PMID: 25808122</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>Adult ; Aged ; Aged, 80 and over ; Carcinoma, Squamous Cell - diagnostic imaging ; Female ; Head & neck cancer ; Head and Neck Neoplasms - diagnostic imaging ; Head and Neck Radiology ; Humans ; Imaging ; Male ; Medicine ; Medicine & Public Health ; Middle Aged ; Neoplasm Recurrence, Local - diagnostic imaging ; Neurology ; Neuroradiology ; Neurosciences ; Neurosurgery ; Observer Variation ; Quality ; Radiation Dosage ; Radiology ; Retrospective Studies ; Signal-To-Noise Ratio ; Tomography ; Tomography, X-Ray Computed - methods ; Young Adult</subject><ispartof>Neuroradiology, 2015-06, Vol.57 (6), p.645-651</ispartof><rights>Springer-Verlag Berlin Heidelberg 2015</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c549t-4d325c21cd80c4d0cedb72ae690486cd43b1dc52cc809375e646ccf295542bff3</citedby><cites>FETCH-LOGICAL-c549t-4d325c21cd80c4d0cedb72ae690486cd43b1dc52cc809375e646ccf295542bff3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00234-015-1512-x$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00234-015-1512-x$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27901,27902,41464,42533,51294</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25808122$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Scholtz, Jan-Erik</creatorcontrib><creatorcontrib>Kaup, Moritz</creatorcontrib><creatorcontrib>Kraft, Johannes</creatorcontrib><creatorcontrib>Nöske, Eva-Maria</creatorcontrib><creatorcontrib>Scheerer, Friedrich</creatorcontrib><creatorcontrib>Schulz, Boris</creatorcontrib><creatorcontrib>Burck, Iris</creatorcontrib><creatorcontrib>Wagenblast, Jens</creatorcontrib><creatorcontrib>Kerl, J. Matthias</creatorcontrib><creatorcontrib>Bauer, Ralf W.</creatorcontrib><creatorcontrib>Lehnert, Thomas</creatorcontrib><creatorcontrib>Vogl, Thomas J.</creatorcontrib><creatorcontrib>Wichmann, Julian L.</creatorcontrib><title>Objective and subjective image quality of primary and recurrent squamous cell carcinoma on head and neck low-tube-voltage 80-kVp computed tomography</title><title>Neuroradiology</title><addtitle>Neuroradiology</addtitle><addtitle>Neuroradiology</addtitle><description>Introduction
To investigate low-tube-voltage 80-kVp computed tomography (CT) of head and neck primary and recurrent squamous cell carcinoma (SCC) regarding objective and subjective image quality.
Methods
We retrospectively evaluated 65 patients (47 male, 18 female; mean age: 62.1 years) who underwent head and neck dual-energy CT (DECT) due to biopsy-proven primary (
n
= 50) or recurrent (
n
= 15) SCC. Eighty peak kilovoltage and standard blended 120-kVp images were compared. Attenuation and noise of malignancy and various soft tissue structures were measured. Tumor signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) were calculated. Subjective image quality was rated by three reviewers using 5-point grading scales regarding overall image quality, lesion delineation, image sharpness, and image noise. Radiation dose was assessed as CT dose index volume (CTDI
vol
). Interobserver agreement was calculated using intraclass correlation coefficient (ICC).
Results
Mean tumor attenuation (153.8 Hounsfield unit (HU) vs. 97.1 HU), SNR (10.7 vs. 8.3), CNR (8.1 vs. 4.8), and subjective tumor delineation (score, 4.46 vs. 4.13) were significantly increased (all
P
< 0.001) with 80-kVp acquisition compared to standard blended 120-kVp images. Noise of all measured structures was increased in 80-kVp acquisition (
P
< 0.001). Overall interobserver agreement was good (ICC, 0.86; 95 % confidence intervals: 0.82–0.89). CTDI
vol
was reduced by 48.7 % with 80-kVp acquisition compared to standard DECT (4.85 ± 0.51 vs. 9.94 ± 0.81 mGy cm,
P
< 0.001).
Conclusions
Head and neck CT with low-tube-voltage 80-kVp acquisition provides increased tumor delineation, SNR, and CNR for CT imaging of primary and recurrent SCC compared to standard 120-kVp acquisition with an accompanying significant reduction of radiation exposure.</description><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Carcinoma, Squamous Cell - diagnostic imaging</subject><subject>Female</subject><subject>Head & neck cancer</subject><subject>Head and Neck Neoplasms - diagnostic imaging</subject><subject>Head and Neck Radiology</subject><subject>Humans</subject><subject>Imaging</subject><subject>Male</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Middle Aged</subject><subject>Neoplasm Recurrence, Local - diagnostic imaging</subject><subject>Neurology</subject><subject>Neuroradiology</subject><subject>Neurosciences</subject><subject>Neurosurgery</subject><subject>Observer Variation</subject><subject>Quality</subject><subject>Radiation Dosage</subject><subject>Radiology</subject><subject>Retrospective Studies</subject><subject>Signal-To-Noise Ratio</subject><subject>Tomography</subject><subject>Tomography, X-Ray Computed - methods</subject><subject>Young Adult</subject><issn>0028-3940</issn><issn>1432-1920</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>BENPR</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNp1kc9u1DAQhy0EokvhAbggS1x6MdiOnThHVPFPqtQLcLWc8WSbbRKndtJ236MPjNNdKoTEybLnm589_gh5K_gHwXn1MXEuC8W40ExoIdn9M7IRqpBM1JI_J5tcNqyoFT8hr1Lacc6LqqhekhOpDTdCyg15uGx2CHN3i9SNnqbladsNbov0ZnF9N-9paOkU81HcP3IRYYkRx5mmTAxhSRSw7ym4CN0YBkfDSK_Q-Ud6RLimfbhj89Iguw39vEYbzq5_TRTCMC0zejqHIWyjm672r8mL1vUJ3xzXU_Lzy-cf59_YxeXX7-efLhhoVc9M-UJqkAK84aA8B_RNJR2WNVemBK-KRnjQEsDwuqg0lqoEaGWttZJN2xan5OyQO8Vws2Ca7dCldQ43Yh7JitJIJY0QMqPv_0F3YYljft1KCaPqSulMiQMFMaQUsbXHT7OC21WZPSizWZldldn73PPumLw0A_qnjj-OMiAPQMqlcYvxr6v_m_obigWj5A</recordid><startdate>20150601</startdate><enddate>20150601</enddate><creator>Scholtz, Jan-Erik</creator><creator>Kaup, Moritz</creator><creator>Kraft, Johannes</creator><creator>Nöske, Eva-Maria</creator><creator>Scheerer, Friedrich</creator><creator>Schulz, Boris</creator><creator>Burck, Iris</creator><creator>Wagenblast, Jens</creator><creator>Kerl, J. Matthias</creator><creator>Bauer, Ralf W.</creator><creator>Lehnert, Thomas</creator><creator>Vogl, Thomas J.</creator><creator>Wichmann, Julian L.</creator><general>Springer Berlin Heidelberg</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QO</scope><scope>7RV</scope><scope>7TK</scope><scope>7U7</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ARAPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB0</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M2O</scope><scope>M7P</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>P5Z</scope><scope>P62</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>7X8</scope></search><sort><creationdate>20150601</creationdate><title>Objective and subjective image quality of primary and recurrent squamous cell carcinoma on head and neck low-tube-voltage 80-kVp computed tomography</title><author>Scholtz, Jan-Erik ; Kaup, Moritz ; Kraft, Johannes ; Nöske, Eva-Maria ; Scheerer, Friedrich ; Schulz, Boris ; Burck, Iris ; Wagenblast, Jens ; Kerl, J. Matthias ; Bauer, Ralf W. ; Lehnert, Thomas ; Vogl, Thomas J. ; Wichmann, Julian L.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c549t-4d325c21cd80c4d0cedb72ae690486cd43b1dc52cc809375e646ccf295542bff3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Carcinoma, Squamous Cell - diagnostic imaging</topic><topic>Female</topic><topic>Head & neck cancer</topic><topic>Head and Neck Neoplasms - diagnostic imaging</topic><topic>Head and Neck Radiology</topic><topic>Humans</topic><topic>Imaging</topic><topic>Male</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Middle Aged</topic><topic>Neoplasm Recurrence, Local - diagnostic imaging</topic><topic>Neurology</topic><topic>Neuroradiology</topic><topic>Neurosciences</topic><topic>Neurosurgery</topic><topic>Observer Variation</topic><topic>Quality</topic><topic>Radiation Dosage</topic><topic>Radiology</topic><topic>Retrospective Studies</topic><topic>Signal-To-Noise Ratio</topic><topic>Tomography</topic><topic>Tomography, X-Ray Computed - methods</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Scholtz, Jan-Erik</creatorcontrib><creatorcontrib>Kaup, Moritz</creatorcontrib><creatorcontrib>Kraft, Johannes</creatorcontrib><creatorcontrib>Nöske, Eva-Maria</creatorcontrib><creatorcontrib>Scheerer, Friedrich</creatorcontrib><creatorcontrib>Schulz, Boris</creatorcontrib><creatorcontrib>Burck, Iris</creatorcontrib><creatorcontrib>Wagenblast, Jens</creatorcontrib><creatorcontrib>Kerl, J. Matthias</creatorcontrib><creatorcontrib>Bauer, Ralf W.</creatorcontrib><creatorcontrib>Lehnert, Thomas</creatorcontrib><creatorcontrib>Vogl, Thomas J.</creatorcontrib><creatorcontrib>Wichmann, Julian L.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Biotechnology Research Abstracts</collection><collection>Nursing & Allied Health Database</collection><collection>Neurosciences Abstracts</collection><collection>Toxicology Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>Advanced Technologies & Aerospace Collection</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Technology Collection</collection><collection>Natural Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Research Library</collection><collection>Biological Science Database</collection><collection>Research Library (Corporate)</collection><collection>Nursing & Allied Health Premium</collection><collection>Advanced Technologies & Aerospace Database</collection><collection>ProQuest Advanced Technologies & Aerospace Collection</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><jtitle>Neuroradiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Scholtz, Jan-Erik</au><au>Kaup, Moritz</au><au>Kraft, Johannes</au><au>Nöske, Eva-Maria</au><au>Scheerer, Friedrich</au><au>Schulz, Boris</au><au>Burck, Iris</au><au>Wagenblast, Jens</au><au>Kerl, J. Matthias</au><au>Bauer, Ralf W.</au><au>Lehnert, Thomas</au><au>Vogl, Thomas J.</au><au>Wichmann, Julian L.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Objective and subjective image quality of primary and recurrent squamous cell carcinoma on head and neck low-tube-voltage 80-kVp computed tomography</atitle><jtitle>Neuroradiology</jtitle><stitle>Neuroradiology</stitle><addtitle>Neuroradiology</addtitle><date>2015-06-01</date><risdate>2015</risdate><volume>57</volume><issue>6</issue><spage>645</spage><epage>651</epage><pages>645-651</pages><issn>0028-3940</issn><eissn>1432-1920</eissn><abstract>Introduction
To investigate low-tube-voltage 80-kVp computed tomography (CT) of head and neck primary and recurrent squamous cell carcinoma (SCC) regarding objective and subjective image quality.
Methods
We retrospectively evaluated 65 patients (47 male, 18 female; mean age: 62.1 years) who underwent head and neck dual-energy CT (DECT) due to biopsy-proven primary (
n
= 50) or recurrent (
n
= 15) SCC. Eighty peak kilovoltage and standard blended 120-kVp images were compared. Attenuation and noise of malignancy and various soft tissue structures were measured. Tumor signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) were calculated. Subjective image quality was rated by three reviewers using 5-point grading scales regarding overall image quality, lesion delineation, image sharpness, and image noise. Radiation dose was assessed as CT dose index volume (CTDI
vol
). Interobserver agreement was calculated using intraclass correlation coefficient (ICC).
Results
Mean tumor attenuation (153.8 Hounsfield unit (HU) vs. 97.1 HU), SNR (10.7 vs. 8.3), CNR (8.1 vs. 4.8), and subjective tumor delineation (score, 4.46 vs. 4.13) were significantly increased (all
P
< 0.001) with 80-kVp acquisition compared to standard blended 120-kVp images. Noise of all measured structures was increased in 80-kVp acquisition (
P
< 0.001). Overall interobserver agreement was good (ICC, 0.86; 95 % confidence intervals: 0.82–0.89). CTDI
vol
was reduced by 48.7 % with 80-kVp acquisition compared to standard DECT (4.85 ± 0.51 vs. 9.94 ± 0.81 mGy cm,
P
< 0.001).
Conclusions
Head and neck CT with low-tube-voltage 80-kVp acquisition provides increased tumor delineation, SNR, and CNR for CT imaging of primary and recurrent SCC compared to standard 120-kVp acquisition with an accompanying significant reduction of radiation exposure.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><pmid>25808122</pmid><doi>10.1007/s00234-015-1512-x</doi><tpages>7</tpages></addata></record> |
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| ispartof | Neuroradiology, 2015-06, Vol.57 (6), p.645-651 |
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| language | eng |
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| source | MEDLINE; SpringerLink Journals - AutoHoldings |
| subjects | Adult Aged Aged, 80 and over Carcinoma, Squamous Cell - diagnostic imaging Female Head & neck cancer Head and Neck Neoplasms - diagnostic imaging Head and Neck Radiology Humans Imaging Male Medicine Medicine & Public Health Middle Aged Neoplasm Recurrence, Local - diagnostic imaging Neurology Neuroradiology Neurosciences Neurosurgery Observer Variation Quality Radiation Dosage Radiology Retrospective Studies Signal-To-Noise Ratio Tomography Tomography, X-Ray Computed - methods Young Adult |
| title | Objective and subjective image quality of primary and recurrent squamous cell carcinoma on head and neck low-tube-voltage 80-kVp computed tomography |
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