Cyclin-dependent kinase 11(p110) (CDK11(p110)) is crucial for human breast cancer cell proliferation and growth

Cyclin-dependent kinases (CDKs) play important roles in the development of many types of cancers by binding with their paired cyclins. However, the function of CDK11 larger protein isomer, CDK11(p110), in the tumorigenesis of human breast cancer remains unclear. In the present study, we explored the...

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Veröffentlicht in:	Scientific reports 2015-05, Vol.5, p.10433
Hauptverfasser:	Zhou, Yubing, Han, Chao, Li, Duolu, Yu, Zujiang, Li, Fengmei, Li, Feng, An, Qi, Bai, Huili, Zhang, Xiaojian, Duan, Zhenfeng, Kan, Quancheng
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis - genetics Breast Neoplasms - genetics Breast Neoplasms - pathology Cell Line, Tumor Cell Movement - genetics Cell Proliferation - genetics Cyclin-Dependent Kinases - biosynthesis Cyclin-Dependent Kinases - genetics Female G1 Phase Cell Cycle Checkpoints - genetics Humans MCF-7 Cells RNA Interference RNA, Small Interfering Tissue Array Analysis
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