IgG4-related Kidney Disease in Which the Urinalysis, Kidney Function and Imaging Findings Were Normal

IgG4-related kidney disease (IgG4RKD) is recognized as a fibroinflammatory disease characterized by storiform fibrosis, lymphoplasmacytic infiltration and a high serum IgG4 level. A renal biopsy is necessary to diagnose IgG4RKD in patients without any lesions in other organs. Nephrologists typically...

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Veröffentlicht in:Internal Medicine 2015, Vol.54(10), pp.1253-1257
Hauptverfasser: Otani, Miho, Morinaga, Masahiro, Nakajima, Yoshihiko, Tomioka, Hiromi, Nishii, Michiko, Inoue, Yusuke, Ikeda, Tetsuya, Morimoto, Mai, Katsuyama, Eiji, Tsunoda, Shinichiro
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container_end_page 1257
container_issue 10
container_start_page 1253
container_title Internal Medicine
container_volume 54
creator Otani, Miho
Morinaga, Masahiro
Nakajima, Yoshihiko
Tomioka, Hiromi
Nishii, Michiko
Inoue, Yusuke
Ikeda, Tetsuya
Morimoto, Mai
Katsuyama, Eiji
Tsunoda, Shinichiro
description IgG4-related kidney disease (IgG4RKD) is recognized as a fibroinflammatory disease characterized by storiform fibrosis, lymphoplasmacytic infiltration and a high serum IgG4 level. A renal biopsy is necessary to diagnose IgG4RKD in patients without any lesions in other organs. Nephrologists typically perform renal biopsies in patients with abnormal urinalysis, such as proteinuria or hematuria, or renal failure. However, we experienced a patient with IgG4RKD without abnormalities in the urinalysis, renal function or imaging, who had severe interstitial lesions. We therefore propose that renal biopsies should be considered if patients do not show abnormal urinalysis findings and are suspected to have IgG4RKD.
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subjects Autoimmune Diseases - diagnosis
Autoimmune Diseases - immunology
Biopsy
Diagnostic Imaging
Humans
IgG4-related kidney disease
Immunoglobulin G - immunology
interstitial nephritis
Kidney Diseases - diagnosis
Kidney Diseases - immunology
Kidney Function Tests
Male
Middle Aged
storiform fibrosis
Urinalysis
title IgG4-related Kidney Disease in Which the Urinalysis, Kidney Function and Imaging Findings Were Normal
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