IgG4-related Kidney Disease in Which the Urinalysis, Kidney Function and Imaging Findings Were Normal
IgG4-related kidney disease (IgG4RKD) is recognized as a fibroinflammatory disease characterized by storiform fibrosis, lymphoplasmacytic infiltration and a high serum IgG4 level. A renal biopsy is necessary to diagnose IgG4RKD in patients without any lesions in other organs. Nephrologists typically...
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Veröffentlicht in: | Internal Medicine 2015, Vol.54(10), pp.1253-1257 |
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creator | Otani, Miho Morinaga, Masahiro Nakajima, Yoshihiko Tomioka, Hiromi Nishii, Michiko Inoue, Yusuke Ikeda, Tetsuya Morimoto, Mai Katsuyama, Eiji Tsunoda, Shinichiro |
description | IgG4-related kidney disease (IgG4RKD) is recognized as a fibroinflammatory disease characterized by storiform fibrosis, lymphoplasmacytic infiltration and a high serum IgG4 level. A renal biopsy is necessary to diagnose IgG4RKD in patients without any lesions in other organs. Nephrologists typically perform renal biopsies in patients with abnormal urinalysis, such as proteinuria or hematuria, or renal failure. However, we experienced a patient with IgG4RKD without abnormalities in the urinalysis, renal function or imaging, who had severe interstitial lesions. We therefore propose that renal biopsies should be considered if patients do not show abnormal urinalysis findings and are suspected to have IgG4RKD. |
doi_str_mv | 10.2169/internalmedicine.54.3259 |
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A renal biopsy is necessary to diagnose IgG4RKD in patients without any lesions in other organs. Nephrologists typically perform renal biopsies in patients with abnormal urinalysis, such as proteinuria or hematuria, or renal failure. However, we experienced a patient with IgG4RKD without abnormalities in the urinalysis, renal function or imaging, who had severe interstitial lesions. We therefore propose that renal biopsies should be considered if patients do not show abnormal urinalysis findings and are suspected to have IgG4RKD.</description><identifier>ISSN: 0918-2918</identifier><identifier>EISSN: 1349-7235</identifier><identifier>DOI: 10.2169/internalmedicine.54.3259</identifier><identifier>PMID: 25986266</identifier><language>eng</language><publisher>Japan: The Japanese Society of Internal Medicine</publisher><subject>Autoimmune Diseases - diagnosis ; Autoimmune Diseases - immunology ; Biopsy ; Diagnostic Imaging ; Humans ; IgG4-related kidney disease ; Immunoglobulin G - immunology ; interstitial nephritis ; Kidney Diseases - diagnosis ; Kidney Diseases - immunology ; Kidney Function Tests ; Male ; Middle Aged ; storiform fibrosis ; Urinalysis</subject><ispartof>Internal Medicine, 2015, Vol.54(10), pp.1253-1257</ispartof><rights>2015 by The Japanese Society of Internal Medicine</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c527t-a86162d4896893db909ddad51aef68302d5bee60de5281e48e2303dc3f3435cd3</citedby><cites>FETCH-LOGICAL-c527t-a86162d4896893db909ddad51aef68302d5bee60de5281e48e2303dc3f3435cd3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,1876,27903,27904</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25986266$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Otani, Miho</creatorcontrib><creatorcontrib>Morinaga, Masahiro</creatorcontrib><creatorcontrib>Nakajima, Yoshihiko</creatorcontrib><creatorcontrib>Tomioka, Hiromi</creatorcontrib><creatorcontrib>Nishii, Michiko</creatorcontrib><creatorcontrib>Inoue, Yusuke</creatorcontrib><creatorcontrib>Ikeda, Tetsuya</creatorcontrib><creatorcontrib>Morimoto, Mai</creatorcontrib><creatorcontrib>Katsuyama, Eiji</creatorcontrib><creatorcontrib>Tsunoda, Shinichiro</creatorcontrib><title>IgG4-related Kidney Disease in Which the Urinalysis, Kidney Function and Imaging Findings Were Normal</title><title>Internal Medicine</title><addtitle>Intern. Med.</addtitle><description>IgG4-related kidney disease (IgG4RKD) is recognized as a fibroinflammatory disease characterized by storiform fibrosis, lymphoplasmacytic infiltration and a high serum IgG4 level. A renal biopsy is necessary to diagnose IgG4RKD in patients without any lesions in other organs. Nephrologists typically perform renal biopsies in patients with abnormal urinalysis, such as proteinuria or hematuria, or renal failure. However, we experienced a patient with IgG4RKD without abnormalities in the urinalysis, renal function or imaging, who had severe interstitial lesions. We therefore propose that renal biopsies should be considered if patients do not show abnormal urinalysis findings and are suspected to have IgG4RKD.</description><subject>Autoimmune Diseases - diagnosis</subject><subject>Autoimmune Diseases - immunology</subject><subject>Biopsy</subject><subject>Diagnostic Imaging</subject><subject>Humans</subject><subject>IgG4-related kidney disease</subject><subject>Immunoglobulin G - immunology</subject><subject>interstitial nephritis</subject><subject>Kidney Diseases - diagnosis</subject><subject>Kidney Diseases - immunology</subject><subject>Kidney Function Tests</subject><subject>Male</subject><subject>Middle Aged</subject><subject>storiform fibrosis</subject><subject>Urinalysis</subject><issn>0918-2918</issn><issn>1349-7235</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNptkD9PIzEUxK0T6Mjl7iucXFKwwf9jlycgXAQiDYjScuyXxGjXC_amyLfHKCEFonlTvN_MSIMQpmTCqDKXMQ2Qk2s7CNHHBBMpJpxJ8wONKBemmTIuT9CIGKobVs8Z-lXKCyFcTw37ic4qqhVTaoRgvr4VTYbWDRDwXQwJdvg6FnAFcEz4eRP9Bg8bwE851sZdieXik5ttkx9in7BLAc87t45pjWcxhaoFP0MG_NDnzrW_0enKtQX-HHSMnmY3j1f_m_vF7fzq333jJZsOjdOKKhaENkobHpaGmBBckNTBSmlOWJBLAEUCSKYpCA2MEx48X3HBpQ98jM73ua-5f9tCGWwXi4e2dQn6bbFUacaIoIJWVO9Rn_tSMqzsa46dyztLif0Y2X4d2UphP0au1r-Hlu2yPo_Gz1UrsNgDL2VwazgCLg_Rt_Btcm2t91BxJP3GZQuJvwPHfprD</recordid><startdate>20150101</startdate><enddate>20150101</enddate><creator>Otani, Miho</creator><creator>Morinaga, Masahiro</creator><creator>Nakajima, Yoshihiko</creator><creator>Tomioka, Hiromi</creator><creator>Nishii, Michiko</creator><creator>Inoue, Yusuke</creator><creator>Ikeda, Tetsuya</creator><creator>Morimoto, Mai</creator><creator>Katsuyama, Eiji</creator><creator>Tsunoda, Shinichiro</creator><general>The Japanese Society of Internal Medicine</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20150101</creationdate><title>IgG4-related Kidney Disease in Which the Urinalysis, Kidney Function and Imaging Findings Were Normal</title><author>Otani, Miho ; Morinaga, Masahiro ; Nakajima, Yoshihiko ; Tomioka, Hiromi ; Nishii, Michiko ; Inoue, Yusuke ; Ikeda, Tetsuya ; Morimoto, Mai ; Katsuyama, Eiji ; Tsunoda, Shinichiro</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c527t-a86162d4896893db909ddad51aef68302d5bee60de5281e48e2303dc3f3435cd3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Autoimmune Diseases - diagnosis</topic><topic>Autoimmune Diseases - immunology</topic><topic>Biopsy</topic><topic>Diagnostic Imaging</topic><topic>Humans</topic><topic>IgG4-related kidney disease</topic><topic>Immunoglobulin G - immunology</topic><topic>interstitial nephritis</topic><topic>Kidney Diseases - diagnosis</topic><topic>Kidney Diseases - immunology</topic><topic>Kidney Function Tests</topic><topic>Male</topic><topic>Middle Aged</topic><topic>storiform fibrosis</topic><topic>Urinalysis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Otani, Miho</creatorcontrib><creatorcontrib>Morinaga, Masahiro</creatorcontrib><creatorcontrib>Nakajima, Yoshihiko</creatorcontrib><creatorcontrib>Tomioka, Hiromi</creatorcontrib><creatorcontrib>Nishii, Michiko</creatorcontrib><creatorcontrib>Inoue, Yusuke</creatorcontrib><creatorcontrib>Ikeda, Tetsuya</creatorcontrib><creatorcontrib>Morimoto, Mai</creatorcontrib><creatorcontrib>Katsuyama, Eiji</creatorcontrib><creatorcontrib>Tsunoda, Shinichiro</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Internal Medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Otani, Miho</au><au>Morinaga, Masahiro</au><au>Nakajima, Yoshihiko</au><au>Tomioka, Hiromi</au><au>Nishii, Michiko</au><au>Inoue, Yusuke</au><au>Ikeda, Tetsuya</au><au>Morimoto, Mai</au><au>Katsuyama, Eiji</au><au>Tsunoda, Shinichiro</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>IgG4-related Kidney Disease in Which the Urinalysis, Kidney Function and Imaging Findings Were Normal</atitle><jtitle>Internal Medicine</jtitle><addtitle>Intern. 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We therefore propose that renal biopsies should be considered if patients do not show abnormal urinalysis findings and are suspected to have IgG4RKD.</abstract><cop>Japan</cop><pub>The Japanese Society of Internal Medicine</pub><pmid>25986266</pmid><doi>10.2169/internalmedicine.54.3259</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Autoimmune Diseases - diagnosis Autoimmune Diseases - immunology Biopsy Diagnostic Imaging Humans IgG4-related kidney disease Immunoglobulin G - immunology interstitial nephritis Kidney Diseases - diagnosis Kidney Diseases - immunology Kidney Function Tests Male Middle Aged storiform fibrosis Urinalysis |
title | IgG4-related Kidney Disease in Which the Urinalysis, Kidney Function and Imaging Findings Were Normal |
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