Reelin Signaling Pathway Genotypes and Alzheimer Disease in a Spanish Population

BACKGROUND:Several reports suggest that the reelin protein could play a role in Alzheimer pathophysiology. This led us to ask whether genetic variability in the reelin pathway may increase the risk of developing Alzheimer disease (AD) or mild cognitive impairment (MCI). METHODS:This was a case-contr...

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Veröffentlicht in:	Alzheimer disease and associated disorders 2015-04, Vol.29 (2), p.169-172
Hauptverfasser:	Bufill, Enric, Roura-Poch, Pere, Sala-Matavera, Isabel, Antón, Sofía, Lleó, Alberto, Sánchez-Saudinós, Belén, Tomàs-Abadal, Lluís, Puig, Teresa, Abós, Josep, Bernades, Santiago, Clarimon, Jordi, Blesa, Rafael
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Alzheimer Disease - genetics Alzheimer Disease - psychology Calcium-Calmodulin-Dependent Protein Kinase Type 2 - genetics Case-Control Studies Cell Adhesion Molecules, Neuronal - genetics Cognitive Dysfunction - genetics Cognitive Dysfunction - psychology Extracellular Matrix Proteins - genetics Female Genotype Humans Male Nerve Tissue Proteins - genetics Polymorphism, Single Nucleotide Protein-Serine-Threonine Kinases - genetics Serine Endopeptidases - genetics Signal Transduction - genetics Spain
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