Effect of Bushenhuoxue formula on interleukin-1 beta and discoidin domain receptor 2 levels in a rat model of osteoarthritis

OBJECTIVE：To determine the effects of Bushenhuoxue formula（BHF） on interleukin-1 beta（IL-1β）,transforming growth factor beta 1（TGF-β1）,discoidin domain receptor 2（DDR2） and matrix metalloproteinase-1（MMP-1） levels in a rat model of osteoarthritis（OA）.METHODS：Sprague-Dawley rats were used to establis...

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Veröffentlicht in:	Journal of Traditional Chinese Medicine 2015-04, Vol.35 (2), p.192-196
Hauptverfasser:	Nianhu, Li, Lei, Xia, Sheng, Yi, Jianhui, Yu, Yi, Zhai, Zhanwang, Xu
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Discoidin Domain Receptors Drugs, Chinese Herbal - administration & dosage Female Humans IL-1β Interleukin-1beta - genetics Interleukin-1beta - metabolism Male Matrix Metalloproteinase 1 - genetics Matrix Metalloproteinase 1 - metabolism Osteoarthritis - drug therapy Osteoarthritis - genetics Osteoarthritis - metabolism Rats Rats, Sprague-Dawley Receptor Protein-Tyrosine Kinases - genetics Receptor Protein-Tyrosine Kinases - metabolism Receptors, Mitogen - genetics Receptors, Mitogen - metabolism SD大鼠 Synovial Fluid - drug effects Synovial Fluid - metabolism 受体盘状结构域补肾活血逆转录聚合酶链反应骨关节炎
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