Targeting the endoplasmic reticulum mediates radiation sensitivity in colorectal cancer

Radiotherapy is an established treatment modality for early and locally advanced rectal cancer as part of short course radiotherapy and long course chemoradiotherapy. The unfolded protein response (UPR) is a cellular stress response pathway often activated in human solid tumours which has been impli...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Experimental and molecular pathology 2015-06, Vol.98 (3), p.532-539
Hauptverfasser:	Drake, T.M., Ritchie, J.E., Kanthou, C., Staves, J.J., Narramore, R., Wyld, L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - metabolism Adenocarcinoma - radiotherapy Cell Line, Tumor Colorectal adenocarcinoma Colorectal cancer Colorectal Neoplasms - metabolism Colorectal Neoplasms - radiotherapy Endoplasmic reticulum Endoplasmic Reticulum - metabolism Endoplasmic Reticulum - radiation effects HT-29 Humans Radiation Tolerance Radiotherapy Unfolded Protein Response X-Rays
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!