Expression and tumorigenicity of the Epstein-Barr virus BARF1 gene in human louckes B-lymphocyte cell line

We previously showed that the Epstein-Barr virus, which encodes the BARF1 gene, could transform rodent fibroblasts. In this work, the expression of the BARF1 gene was studied in the human Louckes B-lymphocyte cell line. Introduction of the BARF1 open reading frame under the control of the Mo-MuLV LT...

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Veröffentlicht in:	Cancer research (Chicago, Ill.) Ill.), 1994-04, Vol.54 (7), p.1843-1848
Hauptverfasser:	WEI, M. X, MOULIN, J.-C, DECAUSSIN, G, BERGER, F, OOKA, T
Format:	Artikel
Sprache:	eng
Schlagworte:	Antigens, CD - biosynthesis B-Lymphocytes - metabolism Biological and medical sciences Burkitt Lymphoma Cell Line Clone Cells Epstein-Barr virus Fluorescent Antibody Technique Gene Expression Gene Expression Regulation, Neoplastic Gene Expression Regulation, Viral Genes, myc Genes, Viral Hematologic and hematopoietic diseases Herpesvirus 4, Human - genetics Herpesvirus 4, Human - metabolism Humans Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis Medical sciences Moloney murine leukemia virus - genetics Open Reading Frames Promoter Regions, Genetic Receptors, Complement 3d - biosynthesis Receptors, IgE - biosynthesis Receptors, Transferrin - biosynthesis Tumor Cells, Cultured Viral Proteins - biosynthesis Viral Proteins - genetics
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