Who should we cool after perinatal asphyxia?
Summary Three ongoing challenges have arisen after the introduction of therapeutic hypothermia (TH) as standard of care for term newborns with moderate or severe perinatal asphyxia: (i) to ensure that the correct group of infants are cooled; (ii) to optimize the delivery of TH and intensive care in...
Gespeichert in:
| Veröffentlicht in: | Seminars in fetal & neonatal medicine 2015-04, Vol.20 (2), p.66-71 |
|---|---|
| 1. Verfasser: | |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 71 |
|---|---|
| container_issue | 2 |
| container_start_page | 66 |
| container_title | Seminars in fetal & neonatal medicine |
| container_volume | 20 |
| creator | Thoresen, Marianne |
| description | Summary Three ongoing challenges have arisen after the introduction of therapeutic hypothermia (TH) as standard of care for term newborns with moderate or severe perinatal asphyxia: (i) to ensure that the correct group of infants are cooled; (ii) to optimize the delivery of TH and intensive care in relation to the severity of the encephalopathy; (iii) to systematically follow up the long-term efficacy of TH using comparable outcome data between centers and countries. This review addresses the entry criteria for TH, and discusses potential issues regarding patient selection, and management of TH: cooling mild, moderate, and very severe perinatal asphyxia, cooling longer or deeper, and/or starting with a greater delay. This includes cooling of patients outside of standard trial entry criteria, such as after postnatal collapse, premature infants, those with infection, and infants with metabolic, chromosomal or surgical diagnoses in addition to perinatal asphyxia. |
| doi_str_mv | 10.1016/j.siny.2015.01.002 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1680958753</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S1744165X15000153</els_id><sourcerecordid>1680958753</sourcerecordid><originalsourceid>FETCH-LOGICAL-c477t-8df43f47bcf4f00b28daae8efd8980bb9e39017c5355cc0fd2a13f38f07ee2ca3</originalsourceid><addsrcrecordid>eNp9kc1v1DAQxS0Eoh_wD3BAOXJowtiOY0dCVFXVL6lSD1CVm-U4Y62XbLzYSWH_exxt4dBDTzMjvfek-T1CPlCoKNDm87pKftxVDKiogFYA7BU5pEqqEtq6eZ13WdclbcSPA3KU0hqAN0rBW3LARNNIyppDcvKwCkVahXnoi99Y2BCGwrgJY7HF6EczmXyn7Wr3x5vTd-SNM0PC90_zmNxfXnw_vy5v765uzs9uS1tLOZWqdzV3teysqx1Ax1RvDCp0vWoVdF2LvAUqreBCWAuuZ4Zyx5UDicis4cfk0z53G8OvGdOkNz5ZHAYzYpiTpo2CVigpeJayvdTGkFJEp7fRb0zcaQp6oaTXeqGkF0oaqM6UsunjU_7cbbD_b_mHJQu-7AWYv3z0GHWyHkeLvY9oJ90H_3L-12d2O_jRWzP8xB2mdZjjmPlpqhPToL8tPS01UQGQYzj_C1uIjW8</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1680958753</pqid></control><display><type>article</type><title>Who should we cool after perinatal asphyxia?</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals</source><creator>Thoresen, Marianne</creator><creatorcontrib>Thoresen, Marianne</creatorcontrib><description>Summary Three ongoing challenges have arisen after the introduction of therapeutic hypothermia (TH) as standard of care for term newborns with moderate or severe perinatal asphyxia: (i) to ensure that the correct group of infants are cooled; (ii) to optimize the delivery of TH and intensive care in relation to the severity of the encephalopathy; (iii) to systematically follow up the long-term efficacy of TH using comparable outcome data between centers and countries. This review addresses the entry criteria for TH, and discusses potential issues regarding patient selection, and management of TH: cooling mild, moderate, and very severe perinatal asphyxia, cooling longer or deeper, and/or starting with a greater delay. This includes cooling of patients outside of standard trial entry criteria, such as after postnatal collapse, premature infants, those with infection, and infants with metabolic, chromosomal or surgical diagnoses in addition to perinatal asphyxia.</description><identifier>ISSN: 1744-165X</identifier><identifier>EISSN: 1878-0946</identifier><identifier>DOI: 10.1016/j.siny.2015.01.002</identifier><identifier>PMID: 25667126</identifier><language>eng</language><publisher>Netherlands: Elsevier Ltd</publisher><subject>Asphyxia Neonatorum - diagnosis ; Asphyxia Neonatorum - therapy ; Clinical trial ; Follow-up ; Human ; Humans ; Hypothermia, Induced - methods ; Hypoxic–ischemic encephalopathy ; Inclusion criteria ; Infant, Newborn ; Infant, Premature ; Neonatal and Perinatal Medicine ; Patient Selection ; Severity of Illness Index ; Therapeutic hypothermia</subject><ispartof>Seminars in fetal & neonatal medicine, 2015-04, Vol.20 (2), p.66-71</ispartof><rights>2015</rights><rights>Copyright © 2015. Published by Elsevier Ltd.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c477t-8df43f47bcf4f00b28daae8efd8980bb9e39017c5355cc0fd2a13f38f07ee2ca3</citedby><cites>FETCH-LOGICAL-c477t-8df43f47bcf4f00b28daae8efd8980bb9e39017c5355cc0fd2a13f38f07ee2ca3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.siny.2015.01.002$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,778,782,3539,27907,27908,45978</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25667126$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Thoresen, Marianne</creatorcontrib><title>Who should we cool after perinatal asphyxia?</title><title>Seminars in fetal & neonatal medicine</title><addtitle>Semin Fetal Neonatal Med</addtitle><description>Summary Three ongoing challenges have arisen after the introduction of therapeutic hypothermia (TH) as standard of care for term newborns with moderate or severe perinatal asphyxia: (i) to ensure that the correct group of infants are cooled; (ii) to optimize the delivery of TH and intensive care in relation to the severity of the encephalopathy; (iii) to systematically follow up the long-term efficacy of TH using comparable outcome data between centers and countries. This review addresses the entry criteria for TH, and discusses potential issues regarding patient selection, and management of TH: cooling mild, moderate, and very severe perinatal asphyxia, cooling longer or deeper, and/or starting with a greater delay. This includes cooling of patients outside of standard trial entry criteria, such as after postnatal collapse, premature infants, those with infection, and infants with metabolic, chromosomal or surgical diagnoses in addition to perinatal asphyxia.</description><subject>Asphyxia Neonatorum - diagnosis</subject><subject>Asphyxia Neonatorum - therapy</subject><subject>Clinical trial</subject><subject>Follow-up</subject><subject>Human</subject><subject>Humans</subject><subject>Hypothermia, Induced - methods</subject><subject>Hypoxic–ischemic encephalopathy</subject><subject>Inclusion criteria</subject><subject>Infant, Newborn</subject><subject>Infant, Premature</subject><subject>Neonatal and Perinatal Medicine</subject><subject>Patient Selection</subject><subject>Severity of Illness Index</subject><subject>Therapeutic hypothermia</subject><issn>1744-165X</issn><issn>1878-0946</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kc1v1DAQxS0Eoh_wD3BAOXJowtiOY0dCVFXVL6lSD1CVm-U4Y62XbLzYSWH_exxt4dBDTzMjvfek-T1CPlCoKNDm87pKftxVDKiogFYA7BU5pEqqEtq6eZ13WdclbcSPA3KU0hqAN0rBW3LARNNIyppDcvKwCkVahXnoi99Y2BCGwrgJY7HF6EczmXyn7Wr3x5vTd-SNM0PC90_zmNxfXnw_vy5v765uzs9uS1tLOZWqdzV3teysqx1Ax1RvDCp0vWoVdF2LvAUqreBCWAuuZ4Zyx5UDicis4cfk0z53G8OvGdOkNz5ZHAYzYpiTpo2CVigpeJayvdTGkFJEp7fRb0zcaQp6oaTXeqGkF0oaqM6UsunjU_7cbbD_b_mHJQu-7AWYv3z0GHWyHkeLvY9oJ90H_3L-12d2O_jRWzP8xB2mdZjjmPlpqhPToL8tPS01UQGQYzj_C1uIjW8</recordid><startdate>20150401</startdate><enddate>20150401</enddate><creator>Thoresen, Marianne</creator><general>Elsevier Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20150401</creationdate><title>Who should we cool after perinatal asphyxia?</title><author>Thoresen, Marianne</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c477t-8df43f47bcf4f00b28daae8efd8980bb9e39017c5355cc0fd2a13f38f07ee2ca3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Asphyxia Neonatorum - diagnosis</topic><topic>Asphyxia Neonatorum - therapy</topic><topic>Clinical trial</topic><topic>Follow-up</topic><topic>Human</topic><topic>Humans</topic><topic>Hypothermia, Induced - methods</topic><topic>Hypoxic–ischemic encephalopathy</topic><topic>Inclusion criteria</topic><topic>Infant, Newborn</topic><topic>Infant, Premature</topic><topic>Neonatal and Perinatal Medicine</topic><topic>Patient Selection</topic><topic>Severity of Illness Index</topic><topic>Therapeutic hypothermia</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Thoresen, Marianne</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Seminars in fetal & neonatal medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Thoresen, Marianne</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Who should we cool after perinatal asphyxia?</atitle><jtitle>Seminars in fetal & neonatal medicine</jtitle><addtitle>Semin Fetal Neonatal Med</addtitle><date>2015-04-01</date><risdate>2015</risdate><volume>20</volume><issue>2</issue><spage>66</spage><epage>71</epage><pages>66-71</pages><issn>1744-165X</issn><eissn>1878-0946</eissn><abstract>Summary Three ongoing challenges have arisen after the introduction of therapeutic hypothermia (TH) as standard of care for term newborns with moderate or severe perinatal asphyxia: (i) to ensure that the correct group of infants are cooled; (ii) to optimize the delivery of TH and intensive care in relation to the severity of the encephalopathy; (iii) to systematically follow up the long-term efficacy of TH using comparable outcome data between centers and countries. This review addresses the entry criteria for TH, and discusses potential issues regarding patient selection, and management of TH: cooling mild, moderate, and very severe perinatal asphyxia, cooling longer or deeper, and/or starting with a greater delay. This includes cooling of patients outside of standard trial entry criteria, such as after postnatal collapse, premature infants, those with infection, and infants with metabolic, chromosomal or surgical diagnoses in addition to perinatal asphyxia.</abstract><cop>Netherlands</cop><pub>Elsevier Ltd</pub><pmid>25667126</pmid><doi>10.1016/j.siny.2015.01.002</doi><tpages>6</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1744-165X |
| ispartof | Seminars in fetal & neonatal medicine, 2015-04, Vol.20 (2), p.66-71 |
| issn | 1744-165X 1878-0946 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1680958753 |
| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Asphyxia Neonatorum - diagnosis Asphyxia Neonatorum - therapy Clinical trial Follow-up Human Humans Hypothermia, Induced - methods Hypoxic–ischemic encephalopathy Inclusion criteria Infant, Newborn Infant, Premature Neonatal and Perinatal Medicine Patient Selection Severity of Illness Index Therapeutic hypothermia |
| title | Who should we cool after perinatal asphyxia? |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-16T20%3A36%3A24IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Who%20should%20we%20cool%20after%20perinatal%20asphyxia?&rft.jtitle=Seminars%20in%20fetal%20&%20neonatal%20medicine&rft.au=Thoresen,%20Marianne&rft.date=2015-04-01&rft.volume=20&rft.issue=2&rft.spage=66&rft.epage=71&rft.pages=66-71&rft.issn=1744-165X&rft.eissn=1878-0946&rft_id=info:doi/10.1016/j.siny.2015.01.002&rft_dat=%3Cproquest_cross%3E1680958753%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1680958753&rft_id=info:pmid/25667126&rft_els_id=S1744165X15000153&rfr_iscdi=true |