An in situ gelling liquid crystalline system based on monoglycerides and polyethylenimine for local delivery of siRNAs

[Display omitted] The development of delivery systems able to complex and release siRNA into the cytosol is essential for therapeutic use of siRNA. Among the delivery systems, local delivery has advantages over systemic administration. In this study, we developed and characterized non-viral carriers...

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Veröffentlicht in:European journal of pharmaceutical sciences 2015-07, Vol.74, p.103-117
Hauptverfasser: Borgheti-Cardoso, Lívia Neves, Depieri, Lívia Vieira, Kooijmans, Sander A.A., Diniz, Henrique, Calzzani, Ricardo Alexandre Junqueira, Vicentini, Fabiana Testa Moura de Carvalho, van der Meel, Roy, Fantini, Márcia Carvalho de Abreu, Iyomasa, Mamie Mizusaki, Schiffelers, Raymond M., Bentley, Maria Vitória Lopes Badra
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Sprache:eng
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