Cell block samples from malignant pleural effusion might be valid alternative samples for anaplastic lymphoma kinase detection in patients with advanced non-small-cell lung cancer

Aim To evaluate the clinical value of cell block samples from malignant pleural effusion (MPE) as alternative samples to tumour tissue for anaplastic lymphoma kinase (ALK) detection in patients with advanced non‐small‐cell lung cancer (NSCLC). Methods and results Fifty‐two matched samples were eligi...

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Veröffentlicht in:	Histopathology 2015-06, Vol.66 (7), p.949-954
Hauptverfasser:	Zhou, Jianya, Yao, Hongtian, Zhao, Jing, Zhang, Shumeng, You, Qihan, Sun, Ke, Zou, Yinying, Zhou, Caicun, Zhou, Jianying
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over anaplastic lymphoma kinase Carcinoma, Non-Small-Cell Lung - metabolism Carcinoma, Non-Small-Cell Lung - pathology Female fluorescence in-situ hybridization Humans Immunohistochemistry In Situ Hybridization, Fluorescence Lung cancer Lung Neoplasms - metabolism Lung Neoplasms - pathology Lymphoma Male Middle Aged pleural effusion Pleural Effusion, Malignant Receptor Protein-Tyrosine Kinases - genetics Receptor Protein-Tyrosine Kinases - metabolism reverse transcription polymerase chain reaction Scandals Sensitivity and Specificity Young Adult
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