Epithelial cell extrusion leads to breaches in the intestinal epithelium

Two distinct forms of intestinal epithelial cell (IEC) extrusion are described: 1 with preserved epithelial integrity and 1 that introduced breaches in the epithelial lining. In this study, we sought to determine the mechanism underlying the IEC extrusion that alters the permeability of the gut epit...

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Veröffentlicht in:	Inflammatory bowel diseases 2013-04, Vol.19 (5), p.912-921
Hauptverfasser:	Liu, Julia J, Davis, Elisabeth M, Wine, Eytan, Lou, Yuefei, Rudzinski, Jan K, Alipour, Misagh, Boulanger, Pierre, Thiesen, Aducio L, Sergi, Consolato, Fedorak, Richard N, Muruve, Daniel, Madsen, Karen L, Irvin, Randall T
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis Blotting, Western Case-Control Studies Caspase 1 - metabolism Caspase 3 - metabolism Cell Differentiation Cell Membrane Permeability Cell Proliferation Cell Surface Extensions - metabolism Cell Surface Extensions - pathology Cells, Cultured Cytokines - metabolism Epithelial Cells - metabolism Epithelial Cells - pathology Escherichia coli Fluorescent Antibody Technique Humans Inflammatory Bowel Diseases - metabolism Inflammatory Bowel Diseases - pathology Interleukin-10 - physiology Intestinal Mucosa - metabolism Intestinal Mucosa - pathology Mice Mice, Inbred C57BL Mice, Knockout
Online-Zugang:	Volltext
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