Brain catalase in the streptozotocin-rat model of sporadic Alzheimer’s disease treated with the iron chelator–monoamine oxidase inhibitor, M30

Low intracerebroventricular (icv) doses of streptozotocin (STZ) produce regionally specific brain neurochemical changes in rats that are similar to those found in the brain of patients with sporadic Alzheimer’s disease (sAD). Since oxidative stress is thought to be one of the major pathologic proces...

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Veröffentlicht in:	Journal of Neural Transmission 2015-04, Vol.122 (4), p.559-564
Hauptverfasser:	Sofic, E., Salkovic-Petrisic, M., Tahirovic, I., Sapcanin, A., Mandel, S., Youdim, M., Riederer, P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer Disease - drug therapy Alzheimer Disease - enzymology Animals Antioxidants - pharmacology Brain - drug effects Brain - enzymology Catalase - metabolism Colorimetry Disease Models, Animal Hydroxyquinolines - pharmacology Iron Chelating Agents - pharmacology Male Medicine Medicine & Public Health Monoamine Oxidase Inhibitors - pharmacology Neurology Neurology and Preclinical Neurological Studies - Original Article Neuroprotective Agents - pharmacology Neurosciences Psychiatry Rats, Wistar Streptozocin
Online-Zugang:	Volltext
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