Impacts of elevated glycaemic haemoglobin and disease duration on the sensorimotor control of hands in diabetes patients
Background To understand the impacts of disease chronicity and hyperglycaemia on sensorimotor control of hands of diabetic patients, this study investigated the differences in hand sensation, strength and motor control by applying the pinch‐holding‐up activity test for patients with diabetes mellitu...
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| Veröffentlicht in: | Diabetes/metabolism research and reviews 2015-05, Vol.31 (4), p.385-394 |
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| creator | Hsu, Hsiu-Yun Chiu, Haw-Yen Lin, Hwai-Ting Su, Fong-Chin Lu, Chieh-Hsiang Kuo, Li-Chieh |
| description | Background
To understand the impacts of disease chronicity and hyperglycaemia on sensorimotor control of hands of diabetic patients, this study investigated the differences in hand sensation, strength and motor control by applying the pinch‐holding‐up activity test for patients with diabetes mellitus (DM) with different levels of glycaemic control and disease chronicity.
Methods
One hundred and fifty‐nine patients with clinically defined DM were included. Semmes–Weinstein monofilament, static two‐point discrimination and moving two‐point discrimination, maximal pinch strength precision pinch performance tests and nerve conduction studies (NCS) of the subjects were carried out. Forty‐seven (29.6%) patients were in the HbA1c 7% group. There were 87 (54.7%) patients with the disease duration |
| doi_str_mv | 10.1002/dmrr.2623 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1680442557</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>3660115111</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4243-6a56ecdbdc0a15f55385e4779538b27357f74076283e1ce0031db50687a4f1f73</originalsourceid><addsrcrecordid>eNqNkV1rFDEUhoMottZe-Ack4I1eTJvvTC-l1rawVVgqvQyZ5Ex36sxkTTK2--_NsOteCEIhcM7F87xw8iL0jpITSgg79UOMJ0wx_gIdUslIpaUiL_e7ZAfoTUoPhBAulHiNDpgUVNdCHaKn62FtXU44tBh6-G0zeHzfb5yFoXN4VUa470PTjdiOHvsugU2A_RRt7sKIy8srwAnGFGI3hBwidmHMMfRz5KpICRfZd7aBDAmviwdjTm_Rq9b2CY538wj9-Hpxe35VLb5fXp9_XlROMMErZaUC5xvviKWylZLXEoTWZ2VpmOZSt1oQrVjNgTooF1LfSKJqbUVLW82P0Mdt7jqGXxOkbIYuOeh7O0KYkqGqJkIwKZ-Dalnwms7oh3_QhzDFsRwyU0LQM6JEoT5tKRdDShFasy5_ZOPGUGLm5szcnJmbK-z7XeLUDOD35N-qCnC6BR67Hjb_TzJfbpbLXWS1NbqU4Wlv2PjTKM21NHffLs0tW1wtOeGm5n8A15Cxyw</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1674419064</pqid></control><display><type>article</type><title>Impacts of elevated glycaemic haemoglobin and disease duration on the sensorimotor control of hands in diabetes patients</title><source>MEDLINE</source><source>Wiley Online Library All Journals</source><creator>Hsu, Hsiu-Yun ; Chiu, Haw-Yen ; Lin, Hwai-Ting ; Su, Fong-Chin ; Lu, Chieh-Hsiang ; Kuo, Li-Chieh</creator><creatorcontrib>Hsu, Hsiu-Yun ; Chiu, Haw-Yen ; Lin, Hwai-Ting ; Su, Fong-Chin ; Lu, Chieh-Hsiang ; Kuo, Li-Chieh</creatorcontrib><description>Background
To understand the impacts of disease chronicity and hyperglycaemia on sensorimotor control of hands of diabetic patients, this study investigated the differences in hand sensation, strength and motor control by applying the pinch‐holding‐up activity test for patients with diabetes mellitus (DM) with different levels of glycaemic control and disease chronicity.
Methods
One hundred and fifty‐nine patients with clinically defined DM were included. Semmes–Weinstein monofilament, static two‐point discrimination and moving two‐point discrimination, maximal pinch strength precision pinch performance tests and nerve conduction studies (NCS) of the subjects were carried out. Forty‐seven (29.6%) patients were in the HbA1c < 7% category, and 112 (70.4%) patients were in the >7% group. There were 87 (54.7%) patients with the disease duration <10 years, and 72 (45.3%) patients with disease duration ≧10 years.
Results
The severity of hyperglycaemia significantly impacts the results for Semmes–Weinstein monofilament, precision pinch force control, sensory and motor NCS tests (p < 0.05). In addition, the chronicity of disease influences the motor control of precision pinch performance and the amplitude of motor NCS (p < 0.05) for the diabetes patients.
Conclusions
The evidence suggests that disease chronicity and hyperglycaemia have impacts on sensorimotor control in the hands of DM patients. In addition, the efficiency of prehensile forces of hand‐to‐object interactions in the pinch‐holding‐up activity test could be significant for identifying hand function, as well as pathologic changes in median nerve function, for patients with DM. Copyright © 2014 John Wiley & Sons, Ltd.</description><identifier>ISSN: 1520-7552</identifier><identifier>EISSN: 1520-7560</identifier><identifier>DOI: 10.1002/dmrr.2623</identifier><identifier>PMID: 25417846</identifier><identifier>CODEN: DMRRFM</identifier><language>eng</language><publisher>England: Blackwell Publishing Ltd</publisher><subject>Aged ; diabetes mellitus ; Diabetes Mellitus - physiopathology ; Diabetes Mellitus - therapy ; Diabetic Neuropathies - blood ; Diabetic Neuropathies - epidemiology ; Diabetic Neuropathies - physiopathology ; Feedback, Sensory ; Female ; Glycated Hemoglobin A - analysis ; Hand ; Hand Strength ; Humans ; hyperglycaemia ; Hyperglycemia - etiology ; Hyperglycemia - physiopathology ; Male ; Median Neuropathy - blood ; Median Neuropathy - complications ; Median Neuropathy - epidemiology ; Median Neuropathy - physiopathology ; Middle Aged ; Motor Skills ; Neural Conduction ; neuropathy ; pinch force adjustment ; Pinch Strength ; Prospective Studies ; Risk Factors ; Severity of Illness Index ; Taiwan - epidemiology ; Up-Regulation</subject><ispartof>Diabetes/metabolism research and reviews, 2015-05, Vol.31 (4), p.385-394</ispartof><rights>Copyright © 2014 John Wiley & Sons, Ltd.</rights><rights>Copyright © 2015 John Wiley & Sons, Ltd.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4243-6a56ecdbdc0a15f55385e4779538b27357f74076283e1ce0031db50687a4f1f73</citedby><cites>FETCH-LOGICAL-c4243-6a56ecdbdc0a15f55385e4779538b27357f74076283e1ce0031db50687a4f1f73</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fdmrr.2623$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fdmrr.2623$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1416,27923,27924,45573,45574</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25417846$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Hsu, Hsiu-Yun</creatorcontrib><creatorcontrib>Chiu, Haw-Yen</creatorcontrib><creatorcontrib>Lin, Hwai-Ting</creatorcontrib><creatorcontrib>Su, Fong-Chin</creatorcontrib><creatorcontrib>Lu, Chieh-Hsiang</creatorcontrib><creatorcontrib>Kuo, Li-Chieh</creatorcontrib><title>Impacts of elevated glycaemic haemoglobin and disease duration on the sensorimotor control of hands in diabetes patients</title><title>Diabetes/metabolism research and reviews</title><addtitle>Diabetes Metab Res Rev</addtitle><description>Background
To understand the impacts of disease chronicity and hyperglycaemia on sensorimotor control of hands of diabetic patients, this study investigated the differences in hand sensation, strength and motor control by applying the pinch‐holding‐up activity test for patients with diabetes mellitus (DM) with different levels of glycaemic control and disease chronicity.
Methods
One hundred and fifty‐nine patients with clinically defined DM were included. Semmes–Weinstein monofilament, static two‐point discrimination and moving two‐point discrimination, maximal pinch strength precision pinch performance tests and nerve conduction studies (NCS) of the subjects were carried out. Forty‐seven (29.6%) patients were in the HbA1c < 7% category, and 112 (70.4%) patients were in the >7% group. There were 87 (54.7%) patients with the disease duration <10 years, and 72 (45.3%) patients with disease duration ≧10 years.
Results
The severity of hyperglycaemia significantly impacts the results for Semmes–Weinstein monofilament, precision pinch force control, sensory and motor NCS tests (p < 0.05). In addition, the chronicity of disease influences the motor control of precision pinch performance and the amplitude of motor NCS (p < 0.05) for the diabetes patients.
Conclusions
The evidence suggests that disease chronicity and hyperglycaemia have impacts on sensorimotor control in the hands of DM patients. In addition, the efficiency of prehensile forces of hand‐to‐object interactions in the pinch‐holding‐up activity test could be significant for identifying hand function, as well as pathologic changes in median nerve function, for patients with DM. Copyright © 2014 John Wiley & Sons, Ltd.</description><subject>Aged</subject><subject>diabetes mellitus</subject><subject>Diabetes Mellitus - physiopathology</subject><subject>Diabetes Mellitus - therapy</subject><subject>Diabetic Neuropathies - blood</subject><subject>Diabetic Neuropathies - epidemiology</subject><subject>Diabetic Neuropathies - physiopathology</subject><subject>Feedback, Sensory</subject><subject>Female</subject><subject>Glycated Hemoglobin A - analysis</subject><subject>Hand</subject><subject>Hand Strength</subject><subject>Humans</subject><subject>hyperglycaemia</subject><subject>Hyperglycemia - etiology</subject><subject>Hyperglycemia - physiopathology</subject><subject>Male</subject><subject>Median Neuropathy - blood</subject><subject>Median Neuropathy - complications</subject><subject>Median Neuropathy - epidemiology</subject><subject>Median Neuropathy - physiopathology</subject><subject>Middle Aged</subject><subject>Motor Skills</subject><subject>Neural Conduction</subject><subject>neuropathy</subject><subject>pinch force adjustment</subject><subject>Pinch Strength</subject><subject>Prospective Studies</subject><subject>Risk Factors</subject><subject>Severity of Illness Index</subject><subject>Taiwan - epidemiology</subject><subject>Up-Regulation</subject><issn>1520-7552</issn><issn>1520-7560</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkV1rFDEUhoMottZe-Ack4I1eTJvvTC-l1rawVVgqvQyZ5Ex36sxkTTK2--_NsOteCEIhcM7F87xw8iL0jpITSgg79UOMJ0wx_gIdUslIpaUiL_e7ZAfoTUoPhBAulHiNDpgUVNdCHaKn62FtXU44tBh6-G0zeHzfb5yFoXN4VUa470PTjdiOHvsugU2A_RRt7sKIy8srwAnGFGI3hBwidmHMMfRz5KpICRfZd7aBDAmviwdjTm_Rq9b2CY538wj9-Hpxe35VLb5fXp9_XlROMMErZaUC5xvviKWylZLXEoTWZ2VpmOZSt1oQrVjNgTooF1LfSKJqbUVLW82P0Mdt7jqGXxOkbIYuOeh7O0KYkqGqJkIwKZ-Dalnwms7oh3_QhzDFsRwyU0LQM6JEoT5tKRdDShFasy5_ZOPGUGLm5szcnJmbK-z7XeLUDOD35N-qCnC6BR67Hjb_TzJfbpbLXWS1NbqU4Wlv2PjTKM21NHffLs0tW1wtOeGm5n8A15Cxyw</recordid><startdate>201505</startdate><enddate>201505</enddate><creator>Hsu, Hsiu-Yun</creator><creator>Chiu, Haw-Yen</creator><creator>Lin, Hwai-Ting</creator><creator>Su, Fong-Chin</creator><creator>Lu, Chieh-Hsiang</creator><creator>Kuo, Li-Chieh</creator><general>Blackwell Publishing Ltd</general><general>Wiley Subscription Services, Inc</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T5</scope><scope>7TK</scope><scope>H94</scope><scope>K9.</scope><scope>7X8</scope></search><sort><creationdate>201505</creationdate><title>Impacts of elevated glycaemic haemoglobin and disease duration on the sensorimotor control of hands in diabetes patients</title><author>Hsu, Hsiu-Yun ; Chiu, Haw-Yen ; Lin, Hwai-Ting ; Su, Fong-Chin ; Lu, Chieh-Hsiang ; Kuo, Li-Chieh</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4243-6a56ecdbdc0a15f55385e4779538b27357f74076283e1ce0031db50687a4f1f73</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Aged</topic><topic>diabetes mellitus</topic><topic>Diabetes Mellitus - physiopathology</topic><topic>Diabetes Mellitus - therapy</topic><topic>Diabetic Neuropathies - blood</topic><topic>Diabetic Neuropathies - epidemiology</topic><topic>Diabetic Neuropathies - physiopathology</topic><topic>Feedback, Sensory</topic><topic>Female</topic><topic>Glycated Hemoglobin A - analysis</topic><topic>Hand</topic><topic>Hand Strength</topic><topic>Humans</topic><topic>hyperglycaemia</topic><topic>Hyperglycemia - etiology</topic><topic>Hyperglycemia - physiopathology</topic><topic>Male</topic><topic>Median Neuropathy - blood</topic><topic>Median Neuropathy - complications</topic><topic>Median Neuropathy - epidemiology</topic><topic>Median Neuropathy - physiopathology</topic><topic>Middle Aged</topic><topic>Motor Skills</topic><topic>Neural Conduction</topic><topic>neuropathy</topic><topic>pinch force adjustment</topic><topic>Pinch Strength</topic><topic>Prospective Studies</topic><topic>Risk Factors</topic><topic>Severity of Illness Index</topic><topic>Taiwan - epidemiology</topic><topic>Up-Regulation</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Hsu, Hsiu-Yun</creatorcontrib><creatorcontrib>Chiu, Haw-Yen</creatorcontrib><creatorcontrib>Lin, Hwai-Ting</creatorcontrib><creatorcontrib>Su, Fong-Chin</creatorcontrib><creatorcontrib>Lu, Chieh-Hsiang</creatorcontrib><creatorcontrib>Kuo, Li-Chieh</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Immunology Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>MEDLINE - Academic</collection><jtitle>Diabetes/metabolism research and reviews</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Hsu, Hsiu-Yun</au><au>Chiu, Haw-Yen</au><au>Lin, Hwai-Ting</au><au>Su, Fong-Chin</au><au>Lu, Chieh-Hsiang</au><au>Kuo, Li-Chieh</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Impacts of elevated glycaemic haemoglobin and disease duration on the sensorimotor control of hands in diabetes patients</atitle><jtitle>Diabetes/metabolism research and reviews</jtitle><addtitle>Diabetes Metab Res Rev</addtitle><date>2015-05</date><risdate>2015</risdate><volume>31</volume><issue>4</issue><spage>385</spage><epage>394</epage><pages>385-394</pages><issn>1520-7552</issn><eissn>1520-7560</eissn><coden>DMRRFM</coden><abstract>Background
To understand the impacts of disease chronicity and hyperglycaemia on sensorimotor control of hands of diabetic patients, this study investigated the differences in hand sensation, strength and motor control by applying the pinch‐holding‐up activity test for patients with diabetes mellitus (DM) with different levels of glycaemic control and disease chronicity.
Methods
One hundred and fifty‐nine patients with clinically defined DM were included. Semmes–Weinstein monofilament, static two‐point discrimination and moving two‐point discrimination, maximal pinch strength precision pinch performance tests and nerve conduction studies (NCS) of the subjects were carried out. Forty‐seven (29.6%) patients were in the HbA1c < 7% category, and 112 (70.4%) patients were in the >7% group. There were 87 (54.7%) patients with the disease duration <10 years, and 72 (45.3%) patients with disease duration ≧10 years.
Results
The severity of hyperglycaemia significantly impacts the results for Semmes–Weinstein monofilament, precision pinch force control, sensory and motor NCS tests (p < 0.05). In addition, the chronicity of disease influences the motor control of precision pinch performance and the amplitude of motor NCS (p < 0.05) for the diabetes patients.
Conclusions
The evidence suggests that disease chronicity and hyperglycaemia have impacts on sensorimotor control in the hands of DM patients. In addition, the efficiency of prehensile forces of hand‐to‐object interactions in the pinch‐holding‐up activity test could be significant for identifying hand function, as well as pathologic changes in median nerve function, for patients with DM. Copyright © 2014 John Wiley & Sons, Ltd.</abstract><cop>England</cop><pub>Blackwell Publishing Ltd</pub><pmid>25417846</pmid><doi>10.1002/dmrr.2623</doi><tpages>10</tpages></addata></record> |
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| subjects | Aged diabetes mellitus Diabetes Mellitus - physiopathology Diabetes Mellitus - therapy Diabetic Neuropathies - blood Diabetic Neuropathies - epidemiology Diabetic Neuropathies - physiopathology Feedback, Sensory Female Glycated Hemoglobin A - analysis Hand Hand Strength Humans hyperglycaemia Hyperglycemia - etiology Hyperglycemia - physiopathology Male Median Neuropathy - blood Median Neuropathy - complications Median Neuropathy - epidemiology Median Neuropathy - physiopathology Middle Aged Motor Skills Neural Conduction neuropathy pinch force adjustment Pinch Strength Prospective Studies Risk Factors Severity of Illness Index Taiwan - epidemiology Up-Regulation |
| title | Impacts of elevated glycaemic haemoglobin and disease duration on the sensorimotor control of hands in diabetes patients |
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