Combined effects of androgen anabolic steroids and physical activity on the hypothalamic–pituitary–gonadal axis

•Distinction of training/doping effects by hormone analytics in male humans possible.•Inhibin B is a sensitive marker for of anabolic substances uptake in male humans.•Anabolic steroids and SARM S-1 decrease prostate weight in intact male rats.•Anabolic steroids and SARM S-1 increase skeletal muscle...

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Veröffentlicht in:	The Journal of steroid biochemistry and molecular biology 2015-06, Vol.150, p.86-96
Hauptverfasser:	Hengevoss, Jonas, Piechotta, Marion, Müller, Dennis, Hanft, Fabian, Parr, Maria Kristina, Schänzer, Wilhelm, Diel, Patrick
Format:	Artikel
Sprache:	eng
Schlagworte:	Amides - pharmacology Anabolic Agents - pharmacology Anabolic steroids Androstenedione - pharmacology Aniline Compounds - pharmacology Animals Estradiol - blood Estrenes - pharmacology Follicle Stimulating Hormone - blood Gonadotropin-Releasing Hormone - blood Humans Hydrocortisone - blood Hypothalamic–pituitary–gonadal axis Hypothalamo-Hypophyseal System - drug effects Hypothalamo-Hypophyseal System - metabolism Inhibins - blood Injections, Subcutaneous Insulin-Like Growth Factor I - metabolism Luteinizing Hormone - blood Male Methandrostenolone - pharmacology Motor Activity Muscle Fibers, Skeletal - drug effects Muscle Fibers, Skeletal - metabolism Pituitary-Adrenal System - drug effects Pituitary-Adrenal System - metabolism Prolactin - blood Rats Rats, Wistar SARMs Testis - drug effects Testis - metabolism Testosterone - blood Thyroxine - blood Training
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