Analysis of influenza A/H3N2 neuraminidase genes obtained from influenza patients in the 2011/12 and 2012/13 seasons in Japan

Influenza virus has neuraminidase (NA), a surface protein with enzymatic activity that is essential for virus replication. Mutation may affect the effectiveness of NA inhibitors that are used for the treatment of influenza patients. In this study, we determined the NA gene sequences from the clinica...

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Veröffentlicht in:	Fukuoka igaku zasshi = Hukuoka acta medica 2015-01, Vol.106 (1), p.16-22
Hauptverfasser:	Ikematsu, Hideyuki, Chong, Yong, Shirane, Kenjiro, Toh, Hidehiro, Sasaki, Hiroyuki, Koga, Yui, Urata, Michiyo, Hotta, Taeko, Uchiumi, Takeshi, Kang, Donchon
Format:	Artikel
Sprache:	jpn
Schlagworte:	Antigens, Viral - genetics Antigens, Viral - immunology Antiviral Agents - pharmacology B-Lymphocytes - immunology Humans Influenza A Virus, H3N2 Subtype - drug effects Influenza A Virus, H3N2 Subtype - enzymology Influenza A Virus, H3N2 Subtype - genetics Influenza A Virus, H3N2 Subtype - isolation & purification Influenza, Human - virology Japan Neuraminidase - genetics Real-Time Polymerase Chain Reaction T-Lymphocytes - immunology
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