Human monocytes and macrophages express NADPH oxidase 5; a potential source of reactive oxygen species in atherosclerosis

Monocytes (Mon) and Mon-derived macrophages (Mac) orchestrate important oxidative and inflammatory reactions in atherosclerosis by secreting reactive oxygen species (ROS) due, in large part, to the upregulated NADPH oxidases (Nox). The Nox enzymes have been extensively investigated in human Mon and...

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Veröffentlicht in:Biochemical and biophysical research communications 2015-05, Vol.461 (1), p.172-179
Hauptverfasser: Manea, Adrian, Manea, Simona-Adriana, Gan, Ana Maria, Constantin, Alina, Fenyo, Ioana Madalina, Raicu, Monica, Muresian, Horia, Simionescu, Maya
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Sprache:eng
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