Convergent evolution of TEM-26, a β-lactamase with extended-spectrum activity

TEM-26, an extended-spectrum β-lactamase has been characterized in clinical isolates of Klebsiella pneumoniae and Escherichia coli derived from patients on the Paediatric Oncology Unit of St James's University Hospital, Leeds. The nucleotide sequence of this β-lactamase gene (blaTEM26b) was det...

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Veröffentlicht in:	Journal of antimicrobial chemotherapy 1994-04, Vol.33 (4), p.707-720
Hauptverfasser:	Hibbert-Rogers, Laura C. F., Heritage, John, Todd, Neil, Hawkey, Peter M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Bacteriology Base Sequence beta-Lactamases - genetics beta-Lactamases - metabolism Biological and medical sciences Biological Evolution Ceftazidime - pharmacology Child Conjugation, Genetic DNA, Bacterial - analysis Drug Resistance, Microbial Escherichia coli Escherichia coli - drug effects Escherichia coli - enzymology Escherichia coli Infections - microbiology Fundamental and applied biological sciences. Psychology Humans Isoelectric Focusing Klebsiella Infections - microbiology Klebsiella oxytoca Klebsiella pneumoniae Klebsiella pneumoniae - drug effects Klebsiella pneumoniae - enzymology Metabolism. Enzymes Microbial Sensitivity Tests Microbiology Molecular Sequence Data Plasmids Polymerase Chain Reaction
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