Rectal bioavailability of Delta -9-tetrahydrocannabinol from the hemisuccinate ester in monkeys

Oral administration of Delta -9-tetrahydrocannabinal ( Delta super(9)-THC) was shown to result in low and erratic bioavailability, while the drug showed no bioavailability from various suppository formulations. Delta super(9)-THC-Hemisuccinate was formulated as a prodrug for Delta super(9)-THC in su...

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Veröffentlicht in:	Journal of pharmaceutical sciences 1991-01, Vol.30 (10), p.942-945
Hauptverfasser:	Elsohly, MA, Stanford, D F, Harland, E C, Hikal, AH, Walker, LA, Little, TL Jr, Rider, J N, Jones, AB
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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