Induction of ER stress-mediated apoptosis by ceramide via disruption of ER Ca(2+) homeostasis in human adenoid cystic carcinoma cells

Ceramides are a class of sphingolipids that form the structural component of the cell membrane and also act as second messengers in cell signaling pathways. Emerging results suggest that ceramide induces growth arrest and apoptosis in various human cancer cells. However, the mechanisms underlying it...

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Veröffentlicht in:Cell & bioscience 2014, Vol.4, p.71-71
Hauptverfasser: Liu, Zhe, Xia, Yichao, Li, Bo, Xu, Hui, Wang, Chenxing, Liu, Ying, Li, Yi, Li, Chunjie, Gao, Ning, Li, Longjiang
Format: Artikel
Sprache:eng
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