The Application of In Vitro Models of Drug Metabolism and Toxicity in Drug Discovery and Drug Development

ABSTRACT In vitro models are being used increasingly during all phases of the drug development process in concert with the more traditional in vivo toxicological and pharmacokinetic evaluations. These in vitro models may be classified empirically as either validated in vitro screens, value-added scr...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Drug and chemical toxicology (New York, N.Y. 1978) N.Y. 1978), 1995-01, Vol.18 (1), p.1-28
Hauptverfasser:	Ball, S. E., Scatina, J. A., Sisenwine, S. F., Fisher, G. L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Drug Evaluation, Preclinical Drug-Related Side Effects and Adverse Reactions General pharmacology Humans In Vitro Techniques Medical sciences Models, Biological Pharmaceutical Preparations - metabolism Pharmacokinetics. Pharmacogenetics. Drug-receptor interactions Pharmacology. Drug treatments Reproducibility of Results Toxicity Tests - methods Toxicity Tests - standards Toxicity Tests - trends
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!