Study on Low-Temperature Deposition Manufacturing Process Parameters of Three-Dimensional Chitosan Scaffold

From the perspective of forming bone scaffold, the technologic parameters of LDM which have important influence on the shape of the deposition material are studied. Through building experimental platform and using chitosan solution as experimental material, the influence of the temperature and the l...

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Veröffentlicht in:Key engineering materials 2012-08, Vol.522, p.97-102
Hauptverfasser: Liu, Da Li, Liu, Ying, Hu, Qing Xi, Han, Zhen Zhong, Liu, Yuan Yuan, Fang, Shu Hui
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Liu, Ying
Hu, Qing Xi
Han, Zhen Zhong
Liu, Yuan Yuan
Fang, Shu Hui
description From the perspective of forming bone scaffold, the technologic parameters of LDM which have important influence on the shape of the deposition material are studied. Through building experimental platform and using chitosan solution as experimental material, the influence of the temperature and the layer height on the lap of every fiber layer are firstly discussed in detail. Besides, the effects of nozzle diameter, the velocity of receiving device, the pressure of feeding device are also discussed. Then the above mentioned process parameters are all optimized, which make the forming mechanism of LDM to be clear. Finally, based on the optimal parameters, the scaffold with self-designed pore size and a high degree of pore interconnectivity, which meeting the requirements of the structure of tissue engineering are fabricated.
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subjects Chitosan
Construction materials
Deposition
Devices
Forming
Porosity
Process parameters
Scaffolds
title Study on Low-Temperature Deposition Manufacturing Process Parameters of Three-Dimensional Chitosan Scaffold
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